Protein Info for PS417_05915 in Pseudomonas simiae WCS417

Annotation: spermidine dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 620 signal peptide" amino acids 7 to 7 (1 residues), see Phobius details transmembrane" amino acids 8 to 26 (19 residues), see Phobius details amino acids 76 to 92 (17 residues), see Phobius details PF13450: NAD_binding_8" amino acids 78 to 136 (59 residues), 43.3 bits, see alignment 3.7e-15

Best Hits

KEGG orthology group: K00316, spermidine dehydrogenase [EC: 1.5.99.6] (inferred from 96% identity to pfs:PFLU1208)

Predicted SEED Role

"FIG00955623: hypothetical protein"

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.5.99.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U5P6 at UniProt or InterPro

Protein Sequence (620 amino acids)

>PS417_05915 spermidine dehydrogenase (Pseudomonas simiae WCS417)
MDITRRDFLNGVAITIAAGMTPLQILQAAPDGRYYPPALTGLRGSHAGSFEVAHQMGWEK
KVFDTDKLPITEDYDLVVVGGGLSGLSAAWFYREKHPKAKILILENHDDFGGHAKRNEFQ
AGGRMIIGYGGSEAFQSPNHLYSKEVNGLLKTLGVNIKRFETAFDRQFYPGLGLSRGVFF
DKENFGEDKLVTGDPTPMVADDVAPGQLNARAIRDFINDFPLPAADRQALIELHMAPKDY
LPGKTAEEKADYLAATSYRDFLLKNVGLSEGAVKYFQSRTNDFMALSIDAVASADAYSVG
FPGFAGMNLAPISEEAAAEMEEPYIYHFPDGNASVARLLVRSLIPGVAPGHTMDDIVLAT
FDYAKLDQPKAAVRLRLNSTAVSVRNVDNGVHIGYSRGGQLAQVRGKRCILACYNMMIPY
LLKDLPAPQAHALSQNVKYPLVYTKVVIRNWQSFQTLGVHEIYAATQPYSRIKLDYPVSM
GGYDHPRDPTQPIGLHMVYVPTSPNSGMNARDQARAGRGKLYGQTFEQLEAQLRDQLQRM
LGPGGFNHETDILAITVNRWSHGYATFSNSLFDDADESEALMKLAKKPVGHVSIANSDAA
WSAYAHAAIDEAYRAAGEVA