Protein Info for GFF1143 in Xanthobacter sp. DMC5

Annotation: Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 396 transmembrane" amino acids 273 to 291 (19 residues), see Phobius details amino acids 297 to 319 (23 residues), see Phobius details amino acids 340 to 362 (23 residues), see Phobius details amino acids 368 to 392 (25 residues), see Phobius details PF13641: Glyco_tranf_2_3" amino acids 40 to 208 (169 residues), 35.2 bits, see alignment E=2e-12 PF00535: Glycos_transf_2" amino acids 43 to 206 (164 residues), 96.1 bits, see alignment E=3.5e-31 PF04138: GtrA_DPMS_TM" amino acids 277 to 392 (116 residues), 58.2 bits, see alignment E=1.4e-19

Best Hits

KEGG orthology group: K00721, dolichol-phosphate mannosyltransferase [EC: 2.4.1.83] (inferred from 69% identity to xau:Xaut_1363)

Predicted SEED Role

"Dolichol-phosphate mannosyltransferase (EC 2.4.1.83) homolog" (EC 2.4.1.83)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.83

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (396 amino acids)

>GFF1143 Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (Xanthobacter sp. DMC5)
MPDSAPAPFGSPYSRGPGIVRQSSAEPESDAAAGVLPAVPRLSVIVPTFNERGNVERMLV
GIDGALAGVPYEVIFVDDDSPDGTADTVRQIGERDPRVRCIRRIGRRGLAGACIEGMLAA
QAPLVAVIDGDLQHDVNVLRTMLYRSPDADLVVASRYVDGGSADGLNRRRGAMSRTATGM
ARRILGIKTSDPMSGCFLIRRALVERLAPSLSPNGFKILLDIMTATKEPMRIVEVPMAFA
ARDEGDSKLDSRTMLDFLTLLIFKVSGGAISPRFVWFSAVGGAGLVLHLLMLKGGLLVGL
GFAVAQSIATIGAMTSNFAMNNVFTYRDRRVSGLAMLPALLKFYLICGAGAVANVGVASW
VFEGGWRWWLAGVAGSVIGAVWNFAMTSLFVWGPSK