Protein Info for GFF1142 in Variovorax sp. SCN45

Annotation: Efflux transport system, outer membrane factor (OMF) lipoprotein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF02321: OEP" amino acids 41 to 261 (221 residues), 50.3 bits, see alignment E=1.3e-17 amino acids 286 to 458 (173 residues), 66.1 bits, see alignment E=1.9e-22

Best Hits

KEGG orthology group: None (inferred from 56% identity to del:DelCs14_2239)

Predicted SEED Role

"Outer membrane protein assembly factor YaeT precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (477 amino acids)

>GFF1142 Efflux transport system, outer membrane factor (OMF) lipoprotein (Variovorax sp. SCN45)
MTSTRPLHSSLLLLPALLMLCGSAFAQAQARSDGTLALSFDAARARMVDRSDKLAAARAA
VDAKELQSQGLKGLGGPTVAVSGLAYAYNANLNLDLDPLNQKLGQIGSALPSSIQSLVSR
VPIPQLPNSYTLNRHDSGANASISAVWPIYLGGATDAVRGFVSAQTREAEADAEQAGHEV
DTLLVQRYFGAQLAQRAATLRAQAERTIAQHDSAAQKMLSAGVISRVERLQASAAYEEAR
RNARKAEDDAALAGVALARTLRADGTVAPQTPLFLISTPIEPLGYFIDSALTRHPGLGKV
AAKKSQAEQLHEGEEALRRPQVIAFGTREIKSGNADWVAGLGVRWTLYDSVDRDALSASS
LKQVEQAERTDAQARSDISLLVERNWRALENARRQYLEMKASVELAQEVVKLRTSGLREG
TSTTLDLIDAETNQAKVLTERAQAANDYVQALAQLLESAGLSEKFSDYIARADVKVN