Protein Info for GFF1124 in Sphingobium sp. HT1-2

Annotation: GumM protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 631 PF13579: Glyco_trans_4_4" amino acids 15 to 172 (158 residues), 60.4 bits, see alignment E=8.2e-20 PF13439: Glyco_transf_4" amino acids 15 to 176 (162 residues), 83.1 bits, see alignment E=7.7e-27 PF20706: GT4-conflict" amino acids 169 to 295 (127 residues), 31.8 bits, see alignment E=2.5e-11 PF00534: Glycos_transf_1" amino acids 188 to 332 (145 residues), 88.8 bits, see alignment E=9.3e-29 PF13692: Glyco_trans_1_4" amino acids 190 to 328 (139 residues), 68.3 bits, see alignment E=2.7e-22 PF03808: Glyco_tran_WecG" amino acids 426 to 591 (166 residues), 182.2 bits, see alignment E=2.2e-57 TIGR00696: glycosyltransferase, WecB/TagA/CpsF family" amino acids 426 to 591 (166 residues), 107.5 bits, see alignment E=3.2e-35

Best Hits

KEGG orthology group: K13657, alpha-1,3-mannosyltransferase [EC: 2.4.1.-] (inferred from 65% identity to sjp:SJA_C2-01960)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.-

Use Curated BLAST to search for 2.4.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (631 amino acids)

>GFF1124 GumM protein (Sphingobium sp. HT1-2)
MKIAHISRQYHPGLGGLESFTRNLCREQARAGHQVRMITLDRIFDGDDAPLPRCEIIDDV
EVVRIPYRGGRRYPLAPSVLHHLDDCDIVHVHAVDFFADYLALTRLLHRKPLVLSTHGGF
FHTGYARRLKQFYFHSMTRLSLAGYRAIIACSEADYETFAKVNRRALTLVENGVDTVKFA
GLAQSPSAEHRFIYFGRIAPNKRIDLLIRWFAHLHRLDRKARLIIAGKPMGVTFADLQQI
VEQLGLGDLVEFHDSPSDEALQALIARSTIFASPSAYEGFGISLIEGVSAGLYPVVSDIP
AHRRSCVKLDTGSLIDFTDPLSAARTLQDIRKAQQRSPSPTTAAGLLAYGWPGVSARISA
IYEHILGRQTRQIGPLRLAVLSESDALKAVSGLIRDQAPRVIAFGNAHLINQARRVEGVA
AALNDALVLNDGVGVDIASRLRYGNSFPHNLNGTDFIPQLLKNYPDRLRLFLVGATPGIA
ERAAAILEERHPHIRIVGTRHGFFDPQEEEHLSRHIRESGADLVIAAMGNPRQELWAAKW
ASHIGRPILCAGALLDFTAGHVPRAPVWLRRMRMEWIFRLMNEPTRLADRYLRGNVTFLM
NAIRDARGGYSDGPIPPSSPHSHAVRNADAA