Protein Info for GFF1106 in Variovorax sp. SCN45

Annotation: UvrD/REP helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1086 PF00580: UvrD-helicase" amino acids 21 to 460 (440 residues), 131.7 bits, see alignment E=1.1e-41 PF13361: UvrD_C" amino acids 561 to 669 (109 residues), 39.1 bits, see alignment E=1.6e-13 amino acids 775 to 872 (98 residues), 40.8 bits, see alignment E=5e-14 PF12705: PDDEXK_1" amino acids 936 to 1069 (134 residues), 32.1 bits, see alignment E=2.9e-11

Best Hits

KEGG orthology group: None (inferred from 90% identity to vpe:Varpa_2503)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1086 amino acids)

>GFF1106 UvrD/REP helicase (Variovorax sp. SCN45)
MNGAAYEHNGRHVTREAFYVVACDPRRSVAVEACAGAGKTWMLVSRILRALLEEGDSACE
PHEILAITFTKKAAGEMRERLDQWLEDFVERTPEELVAQLVMRGVEPAAALAAVPRLKGL
YRRLLEGGRPVQFRTFHAWFAGLLRNAPLAVLRELGLPSNYELLEDDAEARSHTWRPFFE
AVTADRNALADYYAVVATHGRSQTAKALGEALSKRVEFSLADAENAVQHFSAFYPSLDGL
EEPTDALRGSAVRQRWLDRAAALGKESNKTPQKAAEAIIDIFGTGEPEAGALPAALAHLR
KNFFVATEDRLNKNLQKFPAAQEAEAELQVLCGAQAQHAAWLYQQRMTRLTRILIAAFAD
VKRAHGWVDMNDVEQAAQLLLGQSALSGWVQERLDARIAHLLIDEFQDTNPLQWQALYGW
LSAYTGAQGRAPRVFIVGDPKQSIYRFRRAEPQVFIAAKKFVREGLDGELLNCDHTHRNA
RAVVGLVNSAMLAAQDAGEFDGYRAHTTERKDEGELLKLPAIDRDALGAAEAAPADDGML
HWRDSLVTPRVLPEEQLLQKECEQAAQWVAQRIADGTPPRQIMVLARRRSRLSAMQDALR
QRHIPVQQPEKNELHDAPEVQDVVALIDALVSPAHDLSLARALKSPVFGIGDDALVQLAL
RQRERPSFNWFSLIQKSEDLPAELTEAGVKLRKWQRWLMTLPPHDALDAIFNDGDLLAKF
GAAVPAPMRQSALANLRGVLTASLDIDGARFTTPYALVRSLRAGGVRAPSVAAPDAVQLL
TVHGAKGLEADTVLMLDCDAPPPRAQTMGVLVEWKGSDSAPTRFVFLASEKTPPACAAAL
LEEEQRARHREELNGLYVATTRARERLVLSSVRPARANEGSWWTRLEPLCEPTEADEPLV
ALPTESGAGSFSMKKMPEAPVPVEVPSTRKAAATATVDARAAAFGQAMHRLLEWAVPGEP
LPAAHVRAAAREFMLDAQQARGAAALAQRIRAGEGAWVWDDRRVDWHGNEVTLVHEGETL
RIDRLVRERDGGAWWILDYKSAARPERDAALIAQMQRYRAAVQHAYPGATVRVAFLTGQG
ELVNLE