Protein Info for GFF1105 in Variovorax sp. SCN45

Annotation: Helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 854 PF12705: PDDEXK_1" amino acids 598 to 846 (249 residues), 134.5 bits, see alignment E=3.2e-43

Best Hits

KEGG orthology group: None (inferred from 86% identity to vpe:Varpa_2502)

Predicted SEED Role

"Helicase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (854 amino acids)

>GFF1105 Helicase (Variovorax sp. SCN45)
MNEGHPVQALWCDPADGVVARIVRALAERELHAARTVVLVPYAQLMGVARAMWARCGSPG
FVPRFETTHNWARSAGGFVPTGYDIAHDMARDLVTAQALLSQAGFSAERFALAGRVVELA
YQLVPLAAAVSPDDRVGDWAARAAQVAEAGSESEWFRTESALIRIAVAWVATSGYATDVL
QRESTRAQVDALIVLEGFQTDPLTQALCALWGDRALHLSLVPTDAPAETAASHVALDPED
EAERAAACVLRHLAEDRAPVALVATDRALTRRISAQLKAQGVITHDETGWKLSTTRAAAT
LMSSLRACTHDASSDQVLEWLKSGADGDALIIQSLEARLRREGVRDWSAWSAWCALVARS
EKPHDATLMTFTEAIEARRAPMTRSRPLAEWLRALRELLEAGEQWEPLSEDMAGGKVIGA
LWLDAGAHGDDEEFPGGRHTLAEFTAWVRDVLEDASFVPPAGDQAPKVVVLPLYQLLGRA
FGAVVIPGCDDRRLPASPEPPGNWSAAQRADLGLPSRDALEAAQRAAWAMALHNPSCELL
WRQSDANGEPVRPSPLVQALHLDHALRPATDPRLPREVAVQPTEYPKPSGALLPLQNIST
SVYEDLRRCPYRFFALRQLGLRSADELDAEVDKRDFGNWLHAVLGHFHQALTETPTQDAQ
ERAAFIEEAARRATRELGLSDAEFLPFAAAWPAVRDGYLQWLTGHEASGAVFVESEPWKE
QPLGDLRLIGRLDRIDRMPDGQPFVIDYKTESASVSKERVKDPTEDTQLAFYAALVADDT
LRAAYVNVGEKSSGTQTVEQPAVVEARDALVAGIISDFTRIAQGAPLPPLGEGAVCDYCA
ARGLCRKDFWEVAQ