Protein Info for GFF1098 in Xanthobacter sp. DMC5

Annotation: Disulfide bond formation protein B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 162 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 44 to 61 (18 residues), see Phobius details amino acids 70 to 90 (21 residues), see Phobius details amino acids 137 to 157 (21 residues), see Phobius details PF02600: DsbB" amino acids 8 to 153 (146 residues), 126.8 bits, see alignment E=4.9e-41

Best Hits

KEGG orthology group: None (inferred from 79% identity to xau:Xaut_3844)

Predicted SEED Role

"Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation" in subsystem Biogenesis of c-type cytochromes or Periplasmic disulfide interchange

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (162 amino acids)

>GFF1098 Disulfide bond formation protein B (Xanthobacter sp. DMC5)
LYPTTKETASLLLVAGSVMALSAAWYFQLVVGLAPCPLCLDQRIAYYAAIPLGLIAFFLA
RSGRSGPARVLLALLGVAMLANAGLAVYHAGIEWQFWTGPTACTGAPVATSNVLSALKGA
RVPRCDEAAWRMFGLSMAGWNALIALGLAVVGFAGATTGRKA