Protein Info for GFF1093 in Variovorax sp. SCN45

Annotation: Phosphate ABC transporter, permease protein PstC (TC 3.A.1.7.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 360 transmembrane" amino acids 66 to 89 (24 residues), see Phobius details amino acids 110 to 140 (31 residues), see Phobius details amino acids 154 to 179 (26 residues), see Phobius details amino acids 204 to 226 (23 residues), see Phobius details amino acids 266 to 289 (24 residues), see Phobius details amino acids 326 to 346 (21 residues), see Phobius details TIGR02138: phosphate ABC transporter, permease protein PstC" amino acids 57 to 352 (296 residues), 309 bits, see alignment E=1.4e-96 PF00528: BPD_transp_1" amino acids 136 to 348 (213 residues), 49.6 bits, see alignment E=2.1e-17

Best Hits

Swiss-Prot: 63% identical to PSTC_ECOLI: Phosphate transport system permease protein PstC (pstC) from Escherichia coli (strain K12)

KEGG orthology group: K02037, phosphate transport system permease protein (inferred from 95% identity to vpe:Varpa_2490)

MetaCyc: 63% identical to phosphate ABC transporter membrane subunit PstC (Escherichia coli K-12 substr. MG1655)
ABC-27-RXN [EC: 7.3.2.1]; 7.3.2.1 [EC: 7.3.2.1]

Predicted SEED Role

"Phosphate transport system permease protein PstC (TC 3.A.1.7.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism (TC 3.A.1.7.1)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (360 amino acids)

>GFF1093 Phosphate ABC transporter, permease protein PstC (TC 3.A.1.7.1) (Variovorax sp. SCN45)
MSNSSLEDAPLSSLPERPVSSTFPAAGASLDLAAERGRVTAPPPPVKAPRSGPMADRLFG
WAAKGAALLTLAMLIGILVSLIVGAWPAISKYGLGFLTSSVWDPVKEEYGGLVMIYGTLA
TSIIALVIAVPVSFGIALFLTELSPNWLKRPLGTAIELLAAVPSIVYGMWGLLVFGPILS
TWVQQPLQKLLTGVPYLGALVSGPPVGIGILSAGIILAIMIIPFIASVMRDVFEVTPPLL
KESAYGLGSTTWEVVSKVVLPYTKAGVIGGIMLGLGRALGETMAVTFVIGNMNQLNSLSV
FEAANSITSALANEFAEAGAGLHQAALMYLGLVLFFITFVVLSLSKMLLAKMKKSEGTKS