Protein Info for PS417_05500 in Pseudomonas simiae WCS417

Annotation: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 233 TIGR01489: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase" amino acids 5 to 180 (176 residues), 82 bits, see alignment E=5.7e-27 PF12710: HAD" amino acids 6 to 171 (166 residues), 38.2 bits, see alignment E=1.1e-13 TIGR01488: HAD phosphoserine phosphatase-like hydrolase, family IB" amino acids 6 to 172 (167 residues), 58.3 bits, see alignment E=9.5e-20

Best Hits

KEGG orthology group: None (inferred from 95% identity to pfs:PFLU1127)

Predicted SEED Role

"2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase related protein" in subsystem Methionine Salvage

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U5H2 at UniProt or InterPro

Protein Sequence (233 amino acids)

>PS417_05500 2,3-diketo-5-methylthio-1-phosphopentane phosphatase (Pseudomonas simiae WCS417)
MIQWHIVCDFDGTITPTDVIDNVLQRFAGPEWETIEQEWLDGHIGSRECLSRQLALIKAT
PSELLAYFDSVEIDPDFPDFVDHVIGLGASIEVVSDGIEQGIARILSRNYVTLLPILANR
LRQVDQNSWRIDFPYSSDACRAASGNCKCKSTPRHKRVLVIGDGKSDMCVASTADFVFAK
GSLADYCAANHIPHARFDTFAEVTALLAQLPQSLAANATTFTAADNQELFHHV