Protein Info for PS417_05475 in Pseudomonas simiae WCS417
Annotation: arginase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.
Best Hits
KEGG orthology group: None (inferred from 95% identity to pfs:PFLU1122)Predicted SEED Role
"Arginase (EC 3.5.3.1)" in subsystem Arginine and Ornithine Degradation (EC 3.5.3.1)
MetaCyc Pathways
- superpathway of arginine and polyamine biosynthesis (15/17 steps found)
- L-citrulline biosynthesis (8/8 steps found)
- superpathway of L-citrulline metabolism (10/12 steps found)
- L-arginine degradation VI (arginase 2 pathway) (4/4 steps found)
- superpathway of putrescine biosynthesis (4/4 steps found)
- L-Nδ-acetylornithine biosynthesis (6/7 steps found)
- L-arginine degradation I (arginase pathway) (3/3 steps found)
- L-arginine degradation VII (arginase 3 pathway) (2/2 steps found)
- putrescine biosynthesis III (2/2 steps found)
- urea cycle (4/5 steps found)
- superpathway of polyamine biosynthesis I (6/8 steps found)
- superpathway of polyamine biosynthesis II (6/8 steps found)
- L-canavanine degradation I (1/2 steps found)
- superpathway of hyoscyamine (atropine) and scopolamine biosynthesis (4/16 steps found)
KEGG Metabolic Maps
- Arginine and proline metabolism
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Urea cycle and metabolism of amino groups
Isozymes
No predicted isozymesUse Curated BLAST to search for 3.5.3.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A1N7UGP9 at UniProt or InterPro
Protein Sequence (306 amino acids)
>PS417_05475 arginase (Pseudomonas simiae WCS417) MNILDLDHSLTGQAPIARRLASGRATRIDLLDLGPKLRLWSTEKTWRRFAERLAQRPRPT DARPEILFVGSGDYHHLTPAFLADLKEPISLIHFDNHPDWVRFAPKRHCGSWVNRALKMP AIKRIVTLGPCSDDLHNPQLRGGNLAALKRGHLQLFPWQHPPSKVWGRVGDGAGHQQQEN HLYWRNLAELDWAAFLDQMITSLPTEAIWITIDKDVLASEDAATNWDQGGMRLTHLLQAL RALAARKRIIGIDVCGEFATPAFSNAFKRWEAKSDQPPPERWSAEDLQRNAATNEALIDL FEELFP