Protein Info for GFF1062 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Sensory box sensor histidine kinase/response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 754 transmembrane" amino acids 16 to 34 (19 residues), see Phobius details amino acids 187 to 208 (22 residues), see Phobius details PF00512: HisKA" amino acids 242 to 306 (65 residues), 69.9 bits, see alignment E=3e-23 PF02518: HATPase_c" amino acids 354 to 466 (113 residues), 96 bits, see alignment E=4e-31 PF00072: Response_reg" amino acids 497 to 608 (112 residues), 78.8 bits, see alignment E=7.1e-26 PF01627: Hpt" amino acids 660 to 729 (70 residues), 37 bits, see alignment E=6.4e-13

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (754 amino acids)

>GFF1062 Sensory box sensor histidine kinase/response regulator (Hydrogenophaga sp. GW460-11-11-14-LB1)
MNRQPTGFAAWRPRQWALAITALLIVTLTPLGWLQWRQLQMLQDTETQQVDSIMWQAYQL
EYELGRLNQALLEAGAVGSTLQPEDLQERYEIFLSRINLVTEIPRRDLLAAWVGFEPVLQ
KIDHFQRGAEPLFNDPQRLVRDAASLNRLHRAAQDLSPALSELTREANRAVARFVDERND
QLRRQSLLLIGLAAVQVGAMLLFVALLVRHIRQQTRQYANLQNLSQELATARDHAEAANH
AKSVFLANMSHEIRTPFQGMLGMLKLLEDTRLSTEQRDYVRTATDSAQHLLGVVNDILDV
STIESGTLTLSSAPVNLRVMAHEVTNLLGPLANDKGVQMSCQCDDGLPAWVMVDPTRVRQ
ILFNLVNNAMKFTQRGSIEVILEADLSIPDGVRMTVKDSGMGMDQNTVDHLFTRFYQADN
SLRRRVGGSGLGLEISRTLARMMDGDIRVSSQLGKGSIFVVTLRLPRTAAPPAEKVLHLD
DDAWERRRTPVRRLRLLVAEDHPVNLKYLNLLIDRMGHEAVFCENGFEALQILNRESFDV
VLLDYHMPVLDGIATTREIRLLPSPTGQVPIVMVTADVVNDTRERATAAGVTQFAPKPMQ
EADLRRALRRCGVLEGSADTQPGVLELPIRTVRSPQQLIDAQTHAELLTMMPREMFNQLL
DMLFKGPEGTALVLQQALEHEDLKAIVYQAHRLKGSCMLLGLRALIAVAADIEKSGQAGD
IRTLRELSETLRVDIRDTVAALPLMAKAVEIKFI