Protein Info for GFF1033 in Sphingobium sp. HT1-2

Annotation: Tetrapartite efflux system, inner membrane component FusBC-like

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 702 transmembrane" amino acids 13 to 38 (26 residues), see Phobius details amino acids 44 to 62 (19 residues), see Phobius details amino acids 69 to 86 (18 residues), see Phobius details amino acids 92 to 110 (19 residues), see Phobius details amino acids 116 to 132 (17 residues), see Phobius details amino acids 151 to 175 (25 residues), see Phobius details amino acids 376 to 397 (22 residues), see Phobius details amino acids 403 to 420 (18 residues), see Phobius details amino acids 429 to 449 (21 residues), see Phobius details amino acids 455 to 474 (20 residues), see Phobius details amino acids 481 to 504 (24 residues), see Phobius details amino acids 511 to 531 (21 residues), see Phobius details PF04632: FUSC" amino acids 18 to 683 (666 residues), 573.4 bits, see alignment E=7.9e-176 PF13515: FUSC_2" amino acids 30 to 160 (131 residues), 49.6 bits, see alignment E=4.5e-17

Best Hits

KEGG orthology group: None (inferred from 80% identity to sch:Sphch_2093)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (702 amino acids)

>GFF1033 Tetrapartite efflux system, inner membrane component FusBC-like (Sphingobium sp. HT1-2)
MKKAALSAWSERLGVPAALFSLKCFLAAMLALYVALSIGLERPYWAFLTSYIVAQPLAGA
VISKAIFRAIGTIVGAAFSVAIVPPLVNSPELLTLAMAAWLALCVFVSLLDRTPRSYMFV
LAGYSACLIVFPDVDSPQTIFTVATLRVQEIWIGIACGSIVHGVVLPGSITGNLFARVEA
MLRDAERWSRDAIATDPVPGLDAERRRLAQDVTELHQMSIHLPFDISRLAPRVRTVRAMQ
DQLSLLLPLGAAVEDRLAMLKQANGGVVPAQVEQLIADARDWLDHPGTDSATRAAGAQAL
IDRCAALEPAADSHMDWAGMMRLSLYSRLGTLIAVHRDCRDLFDQMLTHSRSPVTPRVAE
LLEGRRNRELHRDYAGAARGAFAAFMTVTIGCALWIGSGWHDGGSAVMLAGVFLALFSAS
DNPLAPLKGFMIGTIIATFLGALYGYAIMPRLDGFAMLALAYAPPLLVLGAMMASPRWMG
IALPTLLGLGSPVLLSSAYVSAFASYVNGSVAQLVGIWFAIIMAGLLQSAGVERAVRRTV
RAGWADIATRANLMTQPDVRGWINRMLDRIALLAPRLAAIRTDSGKPLYDALRDLRTGVA
IGELRQLRVDLPFDEGAPLGRVLGGVADHYRRLDPDAPASADPALLDDIDSAIGDLAANP
APSVRRDAILALVSLRRNLFADSAGYRMPPLTPTTPLTGVPA