Protein Info for PS417_05125 in Pseudomonas simiae WCS417

Annotation: sugar ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 325 transmembrane" amino acids 87 to 109 (23 residues), see Phobius details PF16220: DUF4880" amino acids 11 to 51 (41 residues), 39.4 bits, see alignment 6.7e-14 PF04773: FecR" amino acids 121 to 211 (91 residues), 73.5 bits, see alignment E=2.4e-24 PF16344: FecR_C" amino acids 257 to 313 (57 residues), 30.2 bits, see alignment E=5.7e-11

Best Hits

KEGG orthology group: None (inferred from 90% identity to pfs:PFLU1047)

Predicted SEED Role

"Iron siderophore sensor protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See U1TI96 at UniProt or InterPro

Protein Sequence (325 amino acids)

>PS417_05125 sugar ABC transporter substrate-binding protein (Pseudomonas simiae WCS417)
MNVTPTPAQEQAALAWLSLLHDQPSGGDQATFSQWLRADPAHVEAYAQAQVLWELSEVPA
RKLADEEALVLQGYLNAMNPSKRSRVARWSGALAMAACLLLMVFMGVGWQPSRWVDDFGA
DYVTAPGEVKTVTLADQSQVTLDADSAIAVDFTQGERHIQLRRGAGFFSVTHTGQSFVVE
AGSGEARVLGTQFEVRLQPAGAEVTVLSGRVGVTPSKQGQQQILTAGQQVAYAEGVADAL
HAVDSESRLAWRDGWLNYYKAPLSDVVKDLERYYPGRILLLNKEMGAKRVSGSFPSKDPQ
AVLNALQAVLGFEQHTLLGRMIVVR