Protein Info for GFF1011 in Variovorax sp. SCN45

Annotation: Regulatory protein MerR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 146 PF13411: MerR_1" amino acids 12 to 78 (67 residues), 47.3 bits, see alignment E=9.3e-17

Best Hits

KEGG orthology group: None (inferred from 42% identity to svo:SVI_2115)

Predicted SEED Role

"FemC, factor involved in methicillin resistance / Glutamine synthetase repressor" in subsystem Methicillin resistance in Staphylococci

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (146 amino acids)

>GFF1011 Regulatory protein MerR (Variovorax sp. SCN45)
MKSNPPAPATTYALADLCVLADLPLRTVRYYVQLGIVDRPEGETRAARYGARQLEQLLLI
KKWTAAGVSLERIREMLHSDQQAPIPARPRAPGSVEVRSHLTVADGIEVVIEPGRAGLSP
AQVRDFIQGVMAAFAAVSSADSSEKN