Protein Info for Echvi_4653 in Echinicola vietnamensis KMM 6221, DSM 17526
Annotation: Glutamine phosphoribosylpyrophosphate amidotransferase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.
Best Hits
KEGG orthology group: K00764, amidophosphoribosyltransferase [EC: 2.4.2.14] (inferred from 68% identity to sli:Slin_5971)Predicted SEED Role
"Amidophosphoribosyltransferase (EC 2.4.2.14)" in subsystem De Novo Purine Biosynthesis (EC 2.4.2.14)
MetaCyc Pathways
- superpathway of histidine, purine, and pyrimidine biosynthesis (42/46 steps found)
- superpathway of purine nucleotides de novo biosynthesis I (21/21 steps found)
- superpathway of purine nucleotides de novo biosynthesis II (23/26 steps found)
- 5-aminoimidazole ribonucleotide biosynthesis I (5/5 steps found)
- superpathway of 5-aminoimidazole ribonucleotide biosynthesis (5/6 steps found)
- 5-aminoimidazole ribonucleotide biosynthesis II (4/5 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.4.2.14
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See L0G7I9 at UniProt or InterPro
Protein Sequence (627 amino acids)
>Echvi_4653 Glutamine phosphoribosylpyrophosphate amidotransferase (Echinicola vietnamensis KMM 6221, DSM 17526) MSDQIKHECGIAMVRLRKPLQYYIDKYGTPMYAANRLYVLMQKQINRGQDGAGIANIKIN SKPGTRYISRYRSVDPQAVNYIFGKVAKKFRKAKKLGGEEGLKNADWIKDNVAFSGEVWL GHLRYGTHGENSIETCHPFLRQNNWRSRNLVMAGNFNMTNVEELFGKLVELGQHPKEKTD TVTVMEKIGHFVDEENQRIFNKYKDEYSNNEITEVIERELDVARILRRSCRDFDGGYAMA GIIGNGASFVVRDPSGIRPAYYYADDEIVVIASEKPAIKSAFNIDYNSIQEIKPGHALIV NKDGSFGEHEILSALEKKSCSFERIYFSRGTDPDIYRERKQLGKALIPQILKAIDFDLKN TVFSYIPNTAETAFLGLIEGLEDYLSAKRREILLEGKPHLENIEDLLSFRPRVEKLVNKD VKLRTFITNDNDRDVMVANVYDTTYEVIRSGVDTIVVLDDSIVRGTTLEKSILTTLDKLK PKRIIVVSSAPQIRYPDCYGIDMSKMREFIAFRAALKLLEETGQQYILDEVYDKCVANPD AEENFVKDIYSQFTPQQVSDKIADIITMDQINAEVKVIYQTVENLNKSCPEHLGDWYFTG NFPTEGGMKVVNKSFVNFMEGKVVRAY