Protein Info for Echvi_4422 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Aminopeptidase N

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 610 signal peptide" amino acids 1 to 15 (15 residues), see Phobius details transmembrane" amino acids 428 to 442 (15 residues), see Phobius details PF01433: Peptidase_M1" amino acids 335 to 489 (155 residues), 63 bits, see alignment E=1.6e-21

Best Hits

KEGG orthology group: None (inferred from 64% identity to mtt:Ftrac_0568)

Predicted SEED Role

"Zn-dependent aminopeptidase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G6I9 at UniProt or InterPro

Protein Sequence (610 amino acids)

>Echvi_4422 Aminopeptidase N (Echinicola vietnamensis KMM 6221, DSM 17526)
MLAFSLCCTVGLNAQTTRWQQAVNYKMDVDMDVEKNQYEGHQDLEYTNNSPDTLYRVFYH
LYYNAFQPNSMMDVRSRTIADADRRVQDRIYNLSPEEIGYLKVKSLKMDGKKLDYEHVGT
ILEVTLDQPILPNSTVEFSMDFEGQVPLQIRRAGRDNKEGVRYSMSQWYPKMANYDDQGW
HANPYIGREFYGIWGDFDVRITIDKSYVLGGTGYLQNPEEIGHGYEEEGQKVKRPRGKTL
TWHFKAPQVHDFMWAADPDYTHDKVEMDNGITIHHLYIKNSKTAENWEKLKEYSPKAMAF
LSEHFGQYPYKQYSIIQGGDGGMEYPMSTLITGERSLPSLVGVTVHEMAHSWFQGVLATN
EALYPWMDEGFTTYATNLTMANIFSEEPSDFPQRGAYVGYERLAKSGREEPMTTHSDHYH
TNFAYGAAAYSKGAVFIAQLGYIIGEKNRDRAMLNYFNDWKFKHPKTNDIIREMEKQSGL
ELDWYKEYWVNSTKSIDYAVKSVEAAGDGTKITLQRDGLMPMPIDLVITYEDGSQEMVYL
PLVIQRGNKPEEAGMPKRILTQRWPWTNITKEITLERPFSTIQKVEIDPSKRMADIDREN
NVFPAEVKEE