Protein Info for Echvi_4353 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Arylsulfatase A and related enzymes

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 481 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF00884: Sulfatase" amino acids 32 to 342 (311 residues), 209.5 bits, see alignment E=1.1e-65 PF01663: Phosphodiest" amino acids 34 to 287 (254 residues), 41.4 bits, see alignment E=2.2e-14 PF16347: SGSH_C" amino acids 304 to 453 (150 residues), 33.7 bits, see alignment E=6e-12

Best Hits

KEGG orthology group: None (inferred from 47% identity to rba:RB5378)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G5G8 at UniProt or InterPro

Protein Sequence (481 amino acids)

>Echvi_4353 Arylsulfatase A and related enzymes (Echinicola vietnamensis KMM 6221, DSM 17526)
MSKIIASTLIALALSANVFSQSMELAGPSEKPNVILINVDDLGWKDLGFMGAEFYETPNL
DRLASSGVVFRQAYAGAANCAPSRANMLTGKYGMSHGIYTVHPPDRGDPKTRILIPSHNE
KFIPNGMKTLGHLFKENGYVTGTFGKWHVSVDPLEYGFDYNVAGGPQGHPGRGGYFSPFK
VDHIKPQKEGEYLTDRLTSEAIDFVESHRDTPFFLYLPFYTVHSPLMAKEEDLKRFSSKE
GKPGRNNSTYAAMIYTMDKNVGRLLEKVNELGISENTIVIFTSDNGGIRATSHQDPLRAG
KGSYYEGGIRVPMVISWIGTIQADVNNDPVSQMDLFPTLARIIGDEKEDWDLEGSDITAA
LKGQKMAERDLFWHFPIYLQAYKPLEDQARDPLFRTRPGSVIRSGDWKLHQYFEDGGLEL
YHLGEDLGEKHNVASEHPEVVKGLLDKLVRWRKKYDAPVPTEPNPSYDEKFEKEQRLMLL
K