Protein Info for Echvi_4341 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: BNR/Asp-box repeat.

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13859: BNR_3
  • amino acids 171 to 422 (252 residues), 104.9 bits, E=1.1e-33
• PF13088: BNR_2
  • amino acids 197 to 478 (282 residues), 106.8 bits, E=2.5e-34
• PF02012: BNR
  • amino acids 344 to 354 (11 residues), 13 bits, see alignment (E = 1.8e-05)

Predicted SEED Role

"Sialidase (EC 3.2.1.18)" in subsystem Galactosylceramide and Sulfatide metabolism or Sialic Acid Metabolism (EC 3.2.1.18)

KEGG Metabolic Maps

• Other glycan degradation
• Sphingolipid metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.18

Sequence Analysis Tools

See L0G4S7 at UniProt or InterPro

Protein Sequence (508 amino acids)

>Echvi_4341 BNR/Asp-box repeat. (Echinicola vietnamensis KMM 6221, DSM 17526)
MGSLLIMMVNCTSRPTGAADVVQVTVNQHTVPVIKGQNNDVLSMEFTLKEGDVLEQISLA
TDGAEELEALTVYELEKGTGGNKEPIAALVRVGEKAVVNMDRPLSPGDHKLVVGIQPKKS
ASLKKTLQIGIKDISFGNSGAAIAKQSGSMPLRLATSLRNAGDDGVAAYRIPGLATTKKG
SLIAVYDIRHNSSVDLQEDIDVGMSRSTDGGENWEPMKTIMDMEEWGGKPQKENGIGDPA
ILVDPANNTIYVVALWLHGKPGERAWFSSGAGMSPDETGQLMMVKSHDDGKTWSDPINIT
RQIKKREWKLMFNGPGKGITMRDGTLVFAGQYKDENDMPYSTLIYSQDQGETWHIGTGAK
ANTTEAQVVELNDGSLMLNMRDNRGGARSVAVTKDLGKTWKEHPSSRSALVEPVCMASLI
TYPENRQSMDASHLFFSNPAVTDGRYNMTIKSSKDEGMSWTKGLLLDEGKGWGYSCLTVI
DKEHLGILYESSQAHMTFQIIRTTELIP