Protein Info for Echvi_4335 in Echinicola vietnamensis KMM 6221, DSM 17526
Annotation: N-acetyl-beta-hexosaminidase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"Beta-hexosaminidase (EC 3.2.1.52)" in subsystem Chitin and N-acetylglucosamine utilization or N-Acetyl-Galactosamine and Galactosamine Utilization (EC 3.2.1.52)
MetaCyc Pathways
- chitin degradation II (Vibrio) (3/6 steps found)
- chitin degradation III (Serratia) (3/7 steps found)
- peptidoglycan recycling I (8/14 steps found)
- peptidoglycan recycling II (3/10 steps found)
KEGG Metabolic Maps
- Aminosugars metabolism
- Glycosaminoglycan degradation
- Glycosphingolipid biosynthesis - ganglio series
- Glycosphingolipid biosynthesis - globo series
- Nucleotide sugars metabolism
- Other glycan degradation
Isozymes
Compare fitness of predicted isozymes for: 3.2.1.52
Use Curated BLAST to search for 3.2.1.52
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (681 amino acids)
>Echvi_4335 N-acetyl-beta-hexosaminidase (Echinicola vietnamensis KMM 6221, DSM 17526) MRNTLLSLFSTLCFIGISLQVLGQKENVSKGFVTKKGIEELKEVPVKLIPYPDSVLWERG ERIVVDGLELQGEGNISESLWNECYDIIGEKDFLPTKKNLLIITLEKIPKLEREAYNLMA SQEGVTIQSNTEEGFYYGLKTLRQLIIQENGIHYVPRVKIYDKPRFPIRGFMIDAGRNYQ DLELIKEHLEIMSDYKLNVFHWHLTDRPAWRIESKAYPQLTAAENHREGRNAGSYYSYNE IRELITYAAERKIQVIPEIDMPGHSDSFTKAMGFKMESKEGMEALEVILREFFSEIPKEL APIIHIGSDEVHIPNPAGFIERMVDIVESNGRKAMMWSPGLPASPSVLRQSWGEMDTVGE KHQRFLEIDSRNSYINNAEPMTFVNKLLFKPIGATMEKNDCLGGILCLWHDVNVADQKDV YLNNPVYPGLLTYAWSTWTADILVAPDIFMTTLPPLGSEAADYFNVYEDYLMDHKKRFFG DRAFPYLRQSDRAWKLYGPTDHPMIDLEAIDKWIGEVGEFTQGRGNTIIIRDRFQQGGYF PDIQVGETVVAKTSIFSQEKQEVLAWIAFETPLRANRTYGGIPETGNWDSHGGKIWVNGE PLPSPEWENPGWNPSNTEGWASKKDQEVPWGKDELYWRREPYKLYLEKGRNEVTITIPYT NIYQNCMVTFGIFDKLPYESY