Protein Info for Echvi_4258 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: TonB-linked outer membrane protein, SusC/RagA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1024 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 30 to 1024 (995 residues), 1019.8 bits, see alignment E=0 PF13620: CarboxypepD_reg" amino acids 31 to 101 (71 residues), 34.8 bits, see alignment 3.7e-12 PF13715: CarbopepD_reg_2" amino acids 32 to 113 (82 residues), 62.4 bits, see alignment E=6.8e-21 PF07715: Plug" amino acids 121 to 230 (110 residues), 53.7 bits, see alignment E=5.5e-18 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 206 to 236 (31 residues), 58.8 bits, see alignment (E = 3.5e-20) PF00593: TonB_dep_Rec" amino acids 317 to 989 (673 residues), 34.6 bits, see alignment E=4.3e-12

Best Hits

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G4J7 at UniProt or InterPro

Protein Sequence (1024 amino acids)

>Echvi_4258 TonB-linked outer membrane protein, SusC/RagA family (Echinicola vietnamensis KMM 6221, DSM 17526)
MRRHIQGMGILLFAQLLLLLFHGAAYGQQITVSGTVTSGEDGTTLPGVNILLKGTGKGTI
SDIDGKYSITVPSTGTLVFTFIGYKSREMAIGNRTVLDVEMGPDLQALDEVVVVGFGEQK
KATMTGAVASIGDKELVQSPVANISNSLVGRLPGLIAVQSSGEPGYDQSSLKIRGIATLN
TGAESDPLILVDGVQRSNLNQIDPHEIETLSILKDASATAVFGVRGANGVILITTKTGSK
GKPEINYTANFGLQSPNSLPDLLDSYQYAMLRNEASVNSGQEPYFSESSLELYRNGGDPY
FHPNVDWFDLVLKDYSAQQQHNFNISGGTDNTRYFVSLGYFDQNGAYDVQDVQTAYSANP
KFKRYNFRSNFDIDFNKDFSASVKLSGQFTDSNYPGYGAGEIFFRILNSNPMMNPGVIDG
KLISGVEGLPSSSGSPLDAIVNNGYQRNFGSTMNTNVSLKHKLGFITEGLSVRGMVAYDN
YYQHNVSRSKESMKYRIVKDPEDPTQPVFLPQGMDAPFSFGESYGRNRKTYFEGAVDYSR
SFGQHNITGMALYMQERYTAPGQEYNVPRGYQGLVGRVTYNFKEKYLSEFNMGYNGSENF
PEGKRFGFFPSFSLGWVLTEESFIPTGDFLSYVKIRGSYGEVGNDKIGGARFLYLPSVFY
PNSGGYHFGQYGDNYQWYSGSQEGRVGNPDVTWERAKKFNLGIETGFFGDKLRINADIFA
EKRDNILWYLGTVPDLVQADLPPVNIGKVENKGFELEVNFNDQIGEFKYWVKSNYSLAKN
KILYMDEPNRAHEWLQRTGHPVGQYWGLQSDGFYNTEEELASAPTSAFTAELQVGDIRYV
DQNDDGTIDQYDEVPIGNSNFPQVIYGLSFGGQYKGFDFSVLFQGADRVSTYIDQMGAWA
FDTDWRNATSRHLERWTQERYEQNLPISYPRVELSPTSGKHNYRPSDFWLEDASYIRLKN
AEIAYNFQSRFLNRLGVTNLRVFANGNNLLTWSDMVNFDPEAPAGRGGFYPQMRVYNLGL
NVRF