Protein Info for Echvi_3984 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: alpha-1,2-mannosidase, putative

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 720 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details TIGR01180: putative alpha-1,2-mannosidase" amino acids 6 to 717 (712 residues), 491.2 bits, see alignment E=2.4e-151 PF17678: Glyco_hydro_92N" amino acids 33 to 235 (203 residues), 149 bits, see alignment E=2.1e-47 PF07971: Glyco_hydro_92" amino acids 260 to 717 (458 residues), 442.9 bits, see alignment E=1.6e-136

Best Hits

KEGG orthology group: None (inferred from 68% identity to zpr:ZPR_2159)

Predicted SEED Role

"Alpha-1,2-mannosidase" in subsystem Mannose Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G5A2 at UniProt or InterPro

Protein Sequence (720 amino acids)

>Echvi_3984 alpha-1,2-mannosidase, putative (Echinicola vietnamensis KMM 6221, DSM 17526)
MKRSLSFSLLIILALHLVGCGAVSKEEAGLSRYVNPFIGTAPLTDPAQIGYTPPEGWRVW
AGLTYPGSSLPNAMVQLSPITQFGSGAGYEYEDTEIIGFTHTNKGHWNLCNIPILPISAD
AKAPFKSTFSHDREKASPGYYEVYLEDYQVKARLTSTLRAGVHEYTFENNEGRTILFDLA
KANNGVSDWEISNPSVRTLQGFQRVGRDKVHFYVTLSQDIAAMDVIQEGSKEGYAKIQLA
DGSSAPVVLKIGLSYVSEANAAENLQQEVGDKSFEDIHQLAVKTWDKLLGHIKVKGGSDK
EKTLFYTSLYRSFQWPALRSDVNGQFADERGKTKKADFRYYTLPSLWDTYRNKVVLLSIM
QPAVTADVIQSLVERGTHSGFIPTFFHGDHAAPFITGAYRRGITDFEVEKAYEYLLNNAY
KEGGTRPYIKEYIEKGYISDPAVENPHVETKAKAGVSKTLEFAYDDYSLAQFAKVMGDKE
HYEDLIKRGQNYRNVFDPSVNFMRGRLENGDWISPFNPTYPYYEYMYREANAWQLSFYVP
HDMTGLVELYGGADPFEKKLDTLFSKPWNPEYIARNVSGFMGQYCHGNQPDHEAPFSYYF
VDKPEKSQAIIDKLLADYYGIGEHGLALSGMDDAGEMSSWYTWNAMGLYPLSPADPEYLV
TIPVFEEVEWTMPSGEKLVITNPSGGRSLKGIEVDGKQIDGYFVPHEVLERGGQVTLITE