Protein Info for Echvi_3979 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Thiol-disulfide isomerase and thioredoxins

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 191 transmembrane" amino acids 10 to 28 (19 residues), see Phobius details PF08534: Redoxin" amino acids 60 to 176 (117 residues), 61.5 bits, see alignment E=2.4e-20 PF02630: SCO1-SenC" amino acids 62 to 129 (68 residues), 23.9 bits, see alignment E=1.1e-08 PF00578: AhpC-TSA" amino acids 62 to 168 (107 residues), 64.4 bits, see alignment E=2.9e-21 PF00085: Thioredoxin" amino acids 77 to 130 (54 residues), 32.2 bits, see alignment E=2.7e-11 PF13905: Thioredoxin_8" amino acids 78 to 168 (91 residues), 53.2 bits, see alignment E=1e-17 PF13098: Thioredoxin_2" amino acids 78 to 179 (102 residues), 29.9 bits, see alignment E=1.8e-10

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G598 at UniProt or InterPro

Protein Sequence (191 amino acids)

>Echvi_3979 Thiol-disulfide isomerase and thioredoxins (Echinicola vietnamensis KMM 6221, DSM 17526)
MNWKKEIKSWSVILGVFALLYVMGWYAPIVGKIQSIILSTGLIKPNVEKRYEVGNDFDYS
VKFTDLEGNLVDMQNFRDKTVFINLWATWCPPCRAEMPHIASLYEKLKDQKDIAFLMVSL
DKEVEKPEKYIKAQGFTFPVVHATYGLNASLKHSSIPTTLVISPKGKILFRQEGMSNFDT
EAFRDFLQTQH