Protein Info for Echvi_3702 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: von Willebrand factor type A domain.

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 transmembrane" amino acids 6 to 27 (22 residues), see Phobius details amino acids 48 to 67 (20 residues), see Phobius details amino acids 297 to 316 (20 residues), see Phobius details PF00092: VWA" amino acids 79 to 273 (195 residues), 67.7 bits, see alignment E=1.6e-22 PF13519: VWA_2" amino acids 81 to 191 (111 residues), 57.9 bits, see alignment E=1.4e-19

Best Hits

KEGG orthology group: K07114, uncharacterized protein (inferred from 48% identity to mtt:Ftrac_1205)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G126 at UniProt or InterPro

Protein Sequence (321 amino acids)

>Echvi_3702 von Willebrand factor type A domain. (Echinicola vietnamensis KMM 6221, DSM 17526)
MIWAYPDLTLIGILAAVFGALYFLYLVRFYRINKRLKVKKHRLLMKMGLRIVYFLLFLVA
LAGPSVGNATKEIKQEGKDLFIAIDLSQSMNAADISPSRLQRVKFELKNLIKNFSSDRIG
LIIFSSEAFIQCPLTFDQNVLQLHLDGLNTNLVPNYGTDIAAPLALAIQKFHTDENQDPK
SKSIVLISDGENFGDNLNNILDQLKDEGIRVFSLGVGTEKGSTIPKGNGVIMDESSNAPA
VSKLSSKTLKRIASETNGQYFEISDENQEIPQLISSIEKLEGAVTGSRTVEASANKYFYF
LLAALGLAILDMILPLKTISM