Protein Info for Echvi_3600 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Superfamily II DNA and RNA helicases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 456 PF00270: DEAD" amino acids 28 to 197 (170 residues), 165.8 bits, see alignment E=7.6e-53 PF00271: Helicase_C" amino acids 232 to 338 (107 residues), 109.8 bits, see alignment E=8.5e-36

Best Hits

KEGG orthology group: None (inferred from 60% identity to psn:Pedsa_0406)

Predicted SEED Role

"DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13)" (EC 3.6.4.13)

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G471 at UniProt or InterPro

Protein Sequence (456 amino acids)

>Echvi_3600 Superfamily II DNA and RNA helicases (Echinicola vietnamensis KMM 6221, DSM 17526)
MTSNNFETFNFNESLQEGLDAMGFNKPTPIQQEAIPEILKGKDLIACAQTGTGKTAAFIL
PILHKIAEKGDNQFNTLIIAPTRELAIQIDQQIQGLAYFVGVSSIAIYGGGDGLVWEQQK
KALEHGTEIVVATPGRLIALLAGGKIKLDTLEHLVLDEADRMLDMGFSDDILKIINYLPK
NRQTVLFSATMPPKIRQFSKKIVTDPHEINIAISKTAEGVTQRIYMAHDSQKESLLEHIL
TQKNYEAVIVFASTKDKVKSIFKTLKKKFKVEAFHSDLSQEERETIMSNFKNKTLKILIG
TDIISRGIDVEGIELVINYDTPSDPEDYVHRVGRTARADKKGEAITFVNEKDLFKLHKTQ
NLIGLEIPRVDLPEELGTGPEYREPNARKGNAPSKGNFKKGTQKKQKPRNPRKNVQNKAT
QTSKDSPKPNAKKPASSSKENGQQSGKFRTRRNVTD