Protein Info for Echvi_3559 in Echinicola vietnamensis KMM 6221, DSM 17526
Annotation: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 38% identical to ARLR_STAS1: Response regulator ArlR (arlR) from Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
KEGG orthology group: None (inferred from 71% identity to shg:Sph21_2558)Predicted SEED Role
"DNA-binding response regulator"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See L0G4L7 at UniProt or InterPro
Protein Sequence (242 amino acids)
>Echvi_3559 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain (Echinicola vietnamensis KMM 6221, DSM 17526) MLTLFPYLSRIKPDFYNVKILVIEDEKDLLKAIKNSLEKEHYVVETAEEYYEALDKLFVY DYDCILLDIMLPNGSGLEIMEELKSAGKRENVIIVSAKDSLDDKLKGLDLGADDYLTKPF HLAELNARVKAVLRRKQLDGKNTIEIGNAVLDLDNRELRIGGDMVVLNRKEFDILNYFML NKNRLVSKMALAEHVWGDHTDQADNFDFIYYQIKNLRKRLQEAQANFEIQAVYGIGYKLG EP