Protein Info for Echvi_3558 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: His Kinase A (phosphoacceptor) domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 423 transmembrane" amino acids 7 to 28 (22 residues), see Phobius details amino acids 135 to 157 (23 residues), see Phobius details PF00512: HisKA" amino acids 214 to 278 (65 residues), 34.1 bits, see alignment E=2.3e-12 PF02518: HATPase_c" amino acids 326 to 409 (84 residues), 33.9 bits, see alignment E=3.8e-12

Best Hits

KEGG orthology group: None (inferred from 57% identity to shg:Sph21_2559)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G0Q0 at UniProt or InterPro

Protein Sequence (423 amino acids)

>Echvi_3558 His Kinase A (phosphoacceptor) domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (Echinicola vietnamensis KMM 6221, DSM 17526)
MKLLNQSLTYLSISILLIVSVWSVFFYVNMLDEIYDSIDDGLANYKLLIINKAVEDSTIF
SKHEFGESNYAIRPIEKSEALQVKDSYKDTLMYMLDEDDKEPVRMLTTAFEHEGQYYKLE
VISSMVEEDDLIEDMFWAIFWLYLLLIISVLVVNNIVLKKVWRPFYDFLEQIKNFRVNKD
SPLPTMRTRTKEFIELKHSCDQLINHTLNAYANQKQFTENAAHELQTPLAIITSKLELLL
EKNSMKNVDAAIAADVLQITSRLTQLNKSLLLLSKIENKQFFDNQAISFNKLVEQTIVDF
EDFASFKEVQVKMEVSQEVTATMDRMLANTLINNLIKNAIIHNQAGGEVIIQLQQGKLII
QNTATSGSLDAKCLFKRFYKNGQSQQNTGLGLSIVEAICQLYSFGINYQYIEGKHSFCVE
LEV