Protein Info for Echvi_3426 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: translation initiation factor IF-3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 183 TIGR00168: translation initiation factor IF-3" amino acids 17 to 180 (164 residues), 178.2 bits, see alignment E=5.2e-57 PF05198: IF3_N" amino acids 17 to 86 (70 residues), 103.3 bits, see alignment E=6.2e-34 PF00707: IF3_C" amino acids 95 to 179 (85 residues), 108.9 bits, see alignment E=9.8e-36

Best Hits

Swiss-Prot: 60% identical to IF3_PORGI: Translation initiation factor IF-3 (infC) from Porphyromonas gingivalis (strain ATCC BAA-308 / W83)

KEGG orthology group: K02520, translation initiation factor IF-3 (inferred from 70% identity to mtt:Ftrac_0509)

Predicted SEED Role

"Translation initiation factor 3"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G3S9 at UniProt or InterPro

Protein Sequence (183 amino acids)

>Echvi_3426 translation initiation factor IF-3 (Echinicola vietnamensis KMM 6221, DSM 17526)
MRGRKPFKPRREEPYKVNQKIRAREVRVVGDFVEGGNVVMSTDEAIKIAQQQDLDLVEIS
PNANPPVCKVIDYAKFKYEQKKKQKEIKANAAKTVLKEIRFGPNTDDHDFDFKLKHAINF
LKDGAKVKAYVHFVGRSIVFKERGEMLLLKFAQSLEEYGQVEQLPKMEGKRMNMFVAPKA
SKK