Protein Info for Echvi_2497 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 297 PF01613: Flavin_Reduct" amino acids 25 to 168 (144 residues), 65.1 bits, see alignment E=4.1e-22

Best Hits

KEGG orthology group: None (inferred from 59% identity to hhy:Halhy_2020)

Predicted SEED Role

"Nitrilotriacetate monooxygenase component B (EC 1.14.13.-)" in subsystem Aromatic Amin Catabolism (EC 1.14.13.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.14.13.-

Use Curated BLAST to search for 1.14.13.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FXV5 at UniProt or InterPro

Protein Sequence (297 amino acids)

>Echvi_2497 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family (Echinicola vietnamensis KMM 6221, DSM 17526)
MIKTISPKEVPTATFHRYMLGAIAPRPIAFVSSIDRVGQINLSPFSFFNAFGSNPPVLVF
SPSRRVRDNTTKHTLENVSEVPEVVVNIVNYEMVQQMSLASTEYERGINEFVKAGLTEER
SVFVKPPRVKEAPVAFECKVLEIRPIGEEGGAANLVICEILLIHIDETILTEGGEIAPDK
LDAVARMGGDWYCRANGNALFKVKKPIKTKGIGIDQLPEKVRHSVVLTGNDLGKLGNVEA
LPDEGAVQDYAMRPEIEEMLVRFQNDEESLLFNLHEYAKDLLAADRVEEAWLVLLQG