Protein Info for Echvi_2452 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: ABC-type transport system, involved in lipoprotein release, permease component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 406 transmembrane" amino acids 21 to 47 (27 residues), see Phobius details amino acids 272 to 296 (25 residues), see Phobius details amino acids 323 to 344 (22 residues), see Phobius details amino acids 369 to 394 (26 residues), see Phobius details PF12704: MacB_PCD" amino acids 26 to 240 (215 residues), 60.3 bits, see alignment E=3.3e-20 PF02687: FtsX" amino acids 274 to 397 (124 residues), 61.5 bits, see alignment E=8.3e-21

Best Hits

KEGG orthology group: K09808, lipoprotein-releasing system permease protein (inferred from 50% identity to mtt:Ftrac_3356)

Predicted SEED Role

"ABC transporter, permease protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FXQ9 at UniProt or InterPro

Protein Sequence (406 amino acids)

>Echvi_2452 ABC-type transport system, involved in lipoprotein release, permease component (Echinicola vietnamensis KMM 6221, DSM 17526)
MNLSYFIAKRISFKRTGGFTGTIHQIAVASIAIGLSILIIAFLILGGFKQVVSDKVFSFT
GHYQVHKFTSHNAYENYPSSKDSQFYTSYEDYGYIRHIQDYAYKPGLLKGDEEVQGVVLK
GVSEAFDQEAFSTSMVKGRFIQFGKKGEASNEVVLSRNIADKLMLTVGDKVVMYFVQDPP
RYRRFDIVGIYETYLEDFDDKIIIGDIQTIRNLNGWENDQVGGFEVFLKDPRLIDTKEEE
LYEVIDYDLKVDKVTTMFIQIFDWLKLLNNNVYVFLGLILFVAAFNMIAILFILIMERTQ
MIGLLKAIGSTNRQIRGIFVWNGVRIIGRGMLIGNLIGLGIAWLQDLTHLISLDPANYYM
SYVPIQWNWPIVLGLNALILFVTTLVLFIPAMMISNVRPIKAIRFD