Protein Info for Echvi_2413 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: N-acetyl-beta-hexosaminidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 788 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details amino acids 42 to 46 (5 residues), see Phobius details transmembrane" amino acids 29 to 41 (13 residues), see Phobius details PF02838: Glyco_hydro_20b" amino acids 56 to 180 (125 residues), 77.6 bits, see alignment E=3.6e-25 PF00728: Glyco_hydro_20" amino acids 183 to 531 (349 residues), 351.3 bits, see alignment E=1.8e-108 PF13290: CHB_HEX_C_1" amino acids 583 to 630 (48 residues), 27.6 bits, see alignment 5.7e-10 PF13287: Fn3_assoc" amino acids 586 to 629 (44 residues), 35.2 bits, see alignment 2.6e-12 PF07691: PA14" amino acids 651 to 776 (126 residues), 66.3 bits, see alignment E=6.6e-22

Best Hits

Predicted SEED Role

"Beta-hexosaminidase (EC 3.2.1.52)" in subsystem Chitin and N-acetylglucosamine utilization or N-Acetyl-Galactosamine and Galactosamine Utilization (EC 3.2.1.52)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.52

Use Curated BLAST to search for 3.2.1.52

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G1D5 at UniProt or InterPro

Protein Sequence (788 amino acids)

>Echvi_2413 N-acetyl-beta-hexosaminidase (Echinicola vietnamensis KMM 6221, DSM 17526)
MFGQADSYGNAFLWEKPLWSVISCNMLKGIYLFCGLFLLLSGSFAQSIPDMGKQFPIIPF
PAQLEAGQGEFQLTASTAIVVKAGKLDLSNEVAFLKELLTAQRLEAHTAEEGGIVLAYSD
ALDHKEGYRLEITPTQVLIEASTNAGFFMGIQTLGQLFPVQLEKREKGPLSLPAVKIADA
PKYKWRGMHIDVARHFFTKEYIQKFIDRLARYHFNKLHLHLTDDQGWRLEIKQLPKLTEI
GAWRTFNNHDSICWERAKTNPDMEIDAWNIKEVDGKEVYGGFYTQAEMKEIIAYAAARHI
EVIPEIDMPGHMNAAVRAYPYLTGDQKTDWGELFSSPLNPCQESTYAFAESVLDEVMELF
PSEYVHIGADEVDREFWGTSMCKQWMEDHGIEDVDKLQSYFVNHMEAYVKSKGKQLIVWD
DALAGGISPTAHVMYWRSWVKDAPFTAANNGNDLIMSPVGGGLYFDYAPDKSTLRKVYTV
DIVPEGFTAAQAEKVIGGQANIWTEYIPSEARADYMYMPRMTALAERVWSDPNDFDGYSS
RLNAHYAWMQQQGINYRLPDLTGIADMNMFVGKGTLEVAAPVDFLEIHYTTDGTDPEVTD
PVLDKPLRVRKDTDFKIAAFGPTGNRGDVYEVPFRKTTYLKGKKVKDVQQGLQVAFHKGT
FEQTALMDDHTPDETRVLDKLHIPSDLGQGSFGMEFTGYIHVPEKGIYDFILTSDDGSKL
YIGGREVVDNDGFHSAKEVSGQVALKAGYHPFELDFIEGGGGYTLMLEYLDKAGIRKPVP
ADWLVIEK