Protein Info for Echvi_2197 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Arabinose efflux permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 401 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 48 to 67 (20 residues), see Phobius details amino acids 78 to 97 (20 residues), see Phobius details amino acids 100 to 100 (1 residues), see Phobius details amino acids 109 to 129 (21 residues), see Phobius details amino acids 140 to 160 (21 residues), see Phobius details amino acids 166 to 184 (19 residues), see Phobius details amino acids 213 to 235 (23 residues), see Phobius details amino acids 246 to 264 (19 residues), see Phobius details amino acids 276 to 294 (19 residues), see Phobius details amino acids 300 to 323 (24 residues), see Phobius details amino acids 335 to 358 (24 residues), see Phobius details amino acids 364 to 384 (21 residues), see Phobius details PF07690: MFS_1" amino acids 18 to 195 (178 residues), 124.9 bits, see alignment E=7.3e-40 amino acids 217 to 396 (180 residues), 76.1 bits, see alignment E=5e-25 PF12832: MFS_1_like" amino acids 20 to 362 (343 residues), 45.5 bits, see alignment E=1.2e-15 PF00083: Sugar_tr" amino acids 48 to 204 (157 residues), 39.1 bits, see alignment E=9.1e-14 amino acids 246 to 383 (138 residues), 26.6 bits, see alignment E=5.5e-10 PF05977: MFS_3" amino acids 67 to 380 (314 residues), 34.8 bits, see alignment E=1.4e-12

Best Hits

KEGG orthology group: None (inferred from 59% identity to mtt:Ftrac_1672)

Predicted SEED Role

"major facilitator superfamily MFS_1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FYS2 at UniProt or InterPro

Protein Sequence (401 amino acids)

>Echvi_2197 Arabinose efflux permease (Echinicola vietnamensis KMM 6221, DSM 17526)
MNLQKFLPPFFTLRFLQLCLSSFLFFASFNMIIPELPAYLTSLGGEDYKGLIISLFTLTA
GLSRPFSGKLADRIGRVPVMIFGAGVCLVVSLLYPLISGVAGFLCLRFLHGFSTGFTPTG
ISAYVADIVPFNRRGEAMGLQSLFSSLGMAAGPALGGYIASIHGITPLFYCSSGVALVSI
LLLIRLKETVPETEAFHVGHFKLKKDELFEKSVLSPCFVLFFSYLSFGIILTIIPDFSAS
LNIANKGIFFAVFTLSSLAIRLLAGRASDRYGRIPVLKAATFCLAMAMTATAFSHTKEML
VFSGILFGFSLGMTSPTIAAWTIDLSLSKFRGRGLATMYIALEAGIGIGALGSGWVYGNQ
QERFPLVFLLGTAGAIIAFIYLFITKTASKSPQNDPASPVT