Protein Info for Echvi_2181 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Beta-galactosidase/beta-glucuronidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 704 transmembrane" amino acids 16 to 38 (23 residues), see Phobius details PF02837: Glyco_hydro_2_N" amino acids 49 to 191 (143 residues), 58.2 bits, see alignment E=2.6e-19 PF13364: BetaGal_ABD2" amino acids 88 to 161 (74 residues), 22.7 bits, see alignment E=3.6e-08 PF22666: Glyco_hydro_2_N2" amino acids 95 to 164 (70 residues), 29.9 bits, see alignment E=1.4e-10 PF00703: Glyco_hydro_2" amino acids 209 to 313 (105 residues), 62.4 bits, see alignment E=1.6e-20 PF02836: Glyco_hydro_2_C" amino acids 316 to 605 (290 residues), 77.6 bits, see alignment E=2.5e-25

Best Hits

KEGG orthology group: None (inferred from 53% identity to bfr:BF0030)

Predicted SEED Role

"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.23

Use Curated BLAST to search for 3.2.1.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FYQ9 at UniProt or InterPro

Protein Sequence (704 amino acids)

>Echvi_2181 Beta-galactosidase/beta-glucuronidase (Echinicola vietnamensis KMM 6221, DSM 17526)
MIKSTEFAYFTRRDSLVSILKGLIFLGCYLASLLMATAQSRKEIDFNQAWHFKKGANNYA
KDVGFVGEEWLDISVPHTFNKEDMQLGKDFYTGDGFYKKHFFVPDSLRDNRLFIRFEGVG
SVAEVYVNGRFLGEHRGSFAAFAYELTHSVNYGEENIIMVKANNEARPDIIPVNHFLFPL
YGGIYRPVSLIVTNKVNIKVTDYASPGIYIHQEDVSAQKATVKVKAKLENRGKELVTVDM
VAEVKDAEGVPIETISKQVSISPQGETLVEQEVVMKNPRLWQGVKDPYLYTLSTKLLKDG
KTLDEVKQPLGLRKVEVRAGEGVFLNNKAYPMYGVTRYQDRWGYGNALSHEQHLEDMMLI
KEIGATTIRLAHYQQAEDIYDLADSLGFLVWAEIPFVNRSSGEEGDNAKQQMTELVRQNF
NHPSIYIWGIHNEVYSNTPDGHVAVLSRQLNDIAKTNDPERLTGSVSGYGEMERPANLSG
DVQGMNRYYGWYEGKIGDLEQWVKGLEENYPHYKVMLTEYGADGNMDQSAEHLPTKRNPV
SGEFFPENYQTETHIQQWAIIEDHPYIVASYLWNMFEFAVPMWNRGGVNARNLKGLVTFD
RKRKKDSFYWYKANWNPEPMVYLANRRDYRRTVSKTTVQLFTNLTAVKLMVNGEVVASGR
EGVNDHHRVFDVQLKVGKNFIQVTGTSKEGVQLEDKMEWVLTEN