Protein Info for Echvi_2128 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Small-conductance mechanosensitive channel

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 transmembrane" amino acids 36 to 58 (23 residues), see Phobius details amino acids 79 to 98 (20 residues), see Phobius details amino acids 104 to 126 (23 residues), see Phobius details PF21088: MS_channel_1st" amino acids 82 to 123 (42 residues), 23.3 bits, see alignment 7.8e-09 PF00924: MS_channel_2nd" amino acids 124 to 191 (68 residues), 76.6 bits, see alignment E=1.9e-25 PF21082: MS_channel_3rd" amino acids 199 to 282 (84 residues), 67 bits, see alignment E=2.5e-22

Best Hits

KEGG orthology group: None (inferred from 58% identity to mtt:Ftrac_0701)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FWU2 at UniProt or InterPro

Protein Sequence (300 amino acids)

>Echvi_2128 Small-conductance mechanosensitive channel (Echinicola vietnamensis KMM 6221, DSM 17526)
MEDLLQDVKEDGIGAFLERLNNFLEYTLVTLGSSKLTVGLLIALVFSVFILVIVTEWIKK
IIVHKVLTRYQMDIGTRQSVGTIIRYVLLIGGFVIIIQNSGIDLSALGILAGALGVGIGF
GLQNITNNFISGLIILFERPIKVGDRIEVGDVNGDVIKISSRSTMIVTNDNISIIVPNSQ
FIDSPVINWSHNDRNIRFNFPVGVSYKEDPQKIKSVLMEVATNNDGVLKTPPPDVLFVEY
GDNSINFILRVWTSQYINKPKVLKSQLYYEIFRRFNEEGIEIPFPQRDLHLKSGFEKIGK