Protein Info for Echvi_2105 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: protoheme IX farnesyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 transmembrane" amino acids 25 to 44 (20 residues), see Phobius details amino acids 50 to 73 (24 residues), see Phobius details amino acids 94 to 120 (27 residues), see Phobius details amino acids 125 to 143 (19 residues), see Phobius details amino acids 150 to 170 (21 residues), see Phobius details amino acids 178 to 199 (22 residues), see Phobius details amino acids 220 to 242 (23 residues), see Phobius details amino acids 249 to 268 (20 residues), see Phobius details amino acids 278 to 297 (20 residues), see Phobius details TIGR01473: protoheme IX farnesyltransferase" amino acids 20 to 299 (280 residues), 267.8 bits, see alignment E=7.5e-84 PF01040: UbiA" amino acids 36 to 284 (249 residues), 183.9 bits, see alignment E=1.7e-58

Best Hits

Swiss-Prot: 47% identical to COXX_FLAPJ: Protoheme IX farnesyltransferase (ctaB) from Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)

KEGG orthology group: K02301, protoheme IX farnesyltransferase [EC: 2.5.1.-] (inferred from 63% identity to mtt:Ftrac_3695)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.5.1.-

Use Curated BLAST to search for 2.5.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G014 at UniProt or InterPro

Protein Sequence (301 amino acids)

>Echvi_2105 protoheme IX farnesyltransferase (Echinicola vietnamensis KMM 6221, DSM 17526)
MRTVNLSEASFIDSISIRAKAYYELIKFRLSALVTFSAVFGFVLGDSGAIFSWGTCFALM
IGGFLISGASGAANEILERDYDKLMKRTQNRPLPLNIISVNEAYWFTVLVALVGVSILWF
FTNPLTTGLGILSMLLYVFVYTPLKRVGPVAVFVGAIPGAMPPLLGWTAATGAISYEALI
IFGIQFIWQFPHFWAIAWVSDEDYKKAGFKLLPCGGRKDFNTAIQIMIYTLFLLPLGLLP
SYFGLTGLNSGIVATVCGVLFLAQTFSLMRDCSRKSALKIMFGSFLYLPIVQIAYLLDKV
A