Protein Info for Echvi_2103 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Heme/copper-type cytochrome/quinol oxidases, subunit 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 632 transmembrane" amino acids 44 to 65 (22 residues), see Phobius details amino acids 95 to 120 (26 residues), see Phobius details amino acids 140 to 159 (20 residues), see Phobius details amino acids 190 to 211 (22 residues), see Phobius details amino acids 230 to 256 (27 residues), see Phobius details amino acids 291 to 314 (24 residues), see Phobius details amino acids 326 to 346 (21 residues), see Phobius details amino acids 354 to 375 (22 residues), see Phobius details amino acids 387 to 412 (26 residues), see Phobius details amino acids 425 to 451 (27 residues), see Phobius details amino acids 463 to 489 (27 residues), see Phobius details amino acids 510 to 532 (23 residues), see Phobius details PF00115: COX1" amino acids 40 to 519 (480 residues), 468.9 bits, see alignment E=8.4e-145

Best Hits

KEGG orthology group: K02274, cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 84% identity to mtt:Ftrac_3693)

Predicted SEED Role

"Cytochrome c oxidase polypeptide I (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FWR5 at UniProt or InterPro

Protein Sequence (632 amino acids)

>Echvi_2103 Heme/copper-type cytochrome/quinol oxidases, subunit 1 (Echinicola vietnamensis KMM 6221, DSM 17526)
MAVANISTHGTTAHDHHDDHHEHSDNFITKYIFSTDHKMIGKQFLVTGIVWALIGGFLSI
LFRLQLGFPDMDMTFLKPILGGWIDESGSLDTNFYLALVTMHGTIMVFFVLTAGLSGTFS
NYLIPLQIGARDMASGFMNMLSYWLFFIAGVIMFISLFIETGPAGGGWVIYPPLSALEQA
IPGSGLGMTLWLVSMVFFIASQLMGGINYITTVINLRTRGMSFSRLPLTIWSFFLTAVIG
LLSFPVLFSAALLLVFDRSFGTSFYLSDIYIGGEALPNTGGSAVLFQHLFWFLGHPEVYI
VLLPALGITSEVIATNSRKPIFGYKAMILSMLGITVLSFVVWAHHMFVSGMNPFLGSIFM
FLTLIIAVPSAVKVFNYLTTLWRGNLVFTPAMLFSIGLVSFFISGGLTGIFLGNSAVDIQ
LHDTYFVVAHFHLVMGSASFFGLMAGVYHWFPKMFGKMMDAKLGYIHFWLTFVGVYMVFF
PMHYIGIAGFPRRYYSWTNFNFADMYTDLNMFVSVAAIVTFGAQFIFLFNFFNSMFRGRK
APLNPWRSNTLEWTTPLHPGHGNWPGEIPAVYRWPYDYSKPGAKEDFIPQTVPLSSTPES
NLPHEAEQVKLEREIMAEEGGDVLVANESKES