Protein Info for Echvi_2097 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Fe-S-cluster-containing hydrogenase components 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1029 transmembrane" amino acids 48 to 68 (21 residues), see Phobius details TIGR04519: MoCo/4Fe-4S cofactor protein extended Tat translocation domain" amino acids 6 to 50 (45 residues), 66.9 bits, see alignment (E = 5.9e-23) PF12838: Fer4_7" amino acids 770 to 854 (85 residues), 36.6 bits, see alignment E=1e-12 PF13247: Fer4_11" amino acids 831 to 891 (61 residues), 35.5 bits, see alignment 1.9e-12

Best Hits

Predicted SEED Role

"Molybdopterin oxidoreductase, iron-sulfur binding subunit (EC 1.2.7.-)" (EC 1.2.7.-)

Isozymes

Compare fitness of predicted isozymes for: 1.2.7.-

Use Curated BLAST to search for 1.2.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FZ64 at UniProt or InterPro

Protein Sequence (1029 amino acids)

>Echvi_2097 Fe-S-cluster-containing hydrogenase components 1 (Echinicola vietnamensis KMM 6221, DSM 17526)
MKENKKKYWKGLEQLTNDPEFVKNADREFPEYLPIGGQQEGGASRRDFLKLMGFSLAAAS
LAACEAPVRKAIPYVNKPVDVNPSIPNYYASTFFGGGEYASVVVKTREGRPIKVDGNKLS
PVTKGGTSAIVEASVLSLYDKERLTSPYKNGEKSDWATIDKEVAAKLKAAGNVKVVTNTI
MSPSSEKALKALTDAIGGAEVITYDASSAYGIVKANQTYYGTAVLPNYSFDKADVIVSFG
ADFLGTWIAPIEYSKQYAQGRKISKEHPEMSRHFQFESNLSLTGANADYRTPIKASQSGL
AVLALYNLLAKKAGAPSVKAAGVEVAHLSKAANELWANRGKSLVVSGSNDPNVQVVINAI
NELLGNNNNTISYTKAVNFRQGDDAAIARFTKELASGRVGGVLFYNCNPVYDTPQGEALG
QAIAKAKVSVATNGTMDETASLVQYVAPDHHYLESWNDFHPKAGEYSLSQPAISPLFDTR
QAQESFLTWAGVPTNYYDFLQDNWKELYAGQSEITTFQEFWDRALYNGYYSTPLASETAE
LTPVGDVSSAAAAVNKSYSASSNGAELIIYQKIGIGDGTFANNPWLQEMSDPISKATWDN
YLTVSQKWANENGLKMVEGETKKAKITANGKSLIVPVLIQPGQADGTIGLALGYGRTKAG
RVANGVGVNAYQLLDNSKGFVNNEITSGVSIELTGDTYRIAQTQTHQTYMDRGNVIQEAT
LPEYKEDASAGREMPKIYKDGEFVKPSKISLWNGHKYSQHHWGLAIDMNSCVGCGACTVA
CQVENNVAVVGKEEVLNRREMAWIRIDRYYSSDAEAGDLEGLEKASDNPEVTFQPMMCQH
CNNAPCETVCPVAATTHSSEGLNQMTYNRCIGTRYCANNCPYKVRRFNWFKYHDNKDFSK
VNVAQNDDLGKMVLNPDVTVRARGVMEKCSMCVQRIQAGKLAAKRENRKVKDGEINVACA
VACSTDALVFGDLNDPKSKVSQMLKIEENTTSAVKEVNEERAYHVLEEINVSPNIWYFTK
IRNKDKNEA