Protein Info for Echvi_2016 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 203 transmembrane" amino acids 6 to 30 (25 residues), see Phobius details amino acids 37 to 58 (22 residues), see Phobius details amino acids 78 to 99 (22 residues), see Phobius details amino acids 110 to 134 (25 residues), see Phobius details amino acids 145 to 165 (21 residues), see Phobius details amino acids 177 to 200 (24 residues), see Phobius details TIGR01940: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit" amino acids 2 to 202 (201 residues), 306.1 bits, see alignment E=8.1e-96 PF02508: Rnf-Nqr" amino acids 4 to 201 (198 residues), 194.7 bits, see alignment E=7e-62

Best Hits

Swiss-Prot: 61% identical to NQRE_MARHV: Na(+)-translocating NADH-quinone reductase subunit E (nqrE) from Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)

KEGG orthology group: K00350, Na+-transporting NADH:ubiquinone oxidoreductase subunit E [EC: 1.6.5.-] (inferred from 80% identity to mtt:Ftrac_1550)

Predicted SEED Role

"Na(+)-translocating NADH-quinone reductase subunit E (EC 1.6.5.-)" in subsystem Na(+)-translocating NADH-quinone oxidoreductase and rnf-like group of electron transport complexes (EC 1.6.5.-)

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.-

Use Curated BLAST to search for 1.6.5.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FWI4 at UniProt or InterPro

Protein Sequence (203 amino acids)

>Echvi_2016 NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit (Echinicola vietnamensis KMM 6221, DSM 17526)
MELFSLGIRSIFIDNMVFAYFLGMCSFLAVSKKVSTALGLGAAVIFVLTITVPLNWLLNE
FVLKEGALSFLGESFATIDLTFLRFIMFIAIIAAMVQLVEMVVEKFAPALYGALGIFLPL
IAVNCAILGGSLFMAQRDYTLAEAGVYGFGSGTGFFLAIVALAAIREKLKYSNVPNGLKG
LGITMLITGLMGIAFMSFMGIDL