Protein Info for Echvi_1891 in Echinicola vietnamensis KMM 6221, DSM 17526
Annotation: Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K11996, adenylyltransferase and sulfurtransferase (inferred from 49% identity to zpr:ZPR_2981)Predicted SEED Role
"Sulfur carrier protein adenylyltransferase ThiF" in subsystem Thiamin biosynthesis
MetaCyc Pathways
- superpathway of thiamine diphosphate biosynthesis I (9/10 steps found)
- superpathway of thiamine diphosphate biosynthesis II (9/11 steps found)
- thiazole component of thiamine diphosphate biosynthesis I (5/6 steps found)
- thiazole component of thiamine diphosphate biosynthesis II (5/7 steps found)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See L0FZG9 at UniProt or InterPro
Protein Sequence (360 amino acids)
>Echvi_1891 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 (Echinicola vietnamensis KMM 6221, DSM 17526) MNETRYQKQIRLKSFGKQSQDKLASSSVLIIGAGGLGTPVAQYLNGVGVGTLAIMDQDTV AESNLARQTLFTPEDVGKHKTDVLIQYLRRQNPSTRFINVREFLTPVNALQELADYDLIV DASDNFGTRYLVNDACVMLDKPFIYGALHEFEGQVSVMNYQNGPTYRCLFPEVGDPSAIL NCDENGVLGILPGLIGTYQALEAVKVLTGIGEPLAGKLLIIDTLAQTHLKVGLTSVPENQ SIRKLQENYGQPMCSTDLPVTSLTCEEFWSKREGDSQHQIIDVRNEGEFDSGHLDSAQNI PLSQLTERHQEINEKAPVILICQSGKRSLQAAQLLQSLHPEQIIYNLEGGMNALEAEDWK