Protein Info for Echvi_1812 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: membrane protein, MarC family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 192 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 42 to 65 (24 residues), see Phobius details amino acids 72 to 93 (22 residues), see Phobius details amino acids 105 to 126 (22 residues), see Phobius details amino acids 132 to 150 (19 residues), see Phobius details amino acids 171 to 189 (19 residues), see Phobius details PF01914: MarC" amino acids 5 to 186 (182 residues), 120.2 bits, see alignment E=4.1e-39 TIGR00427: membrane protein, MarC family" amino acids 7 to 185 (179 residues), 104.7 bits, see alignment E=2.6e-34

Best Hits

KEGG orthology group: K05595, multiple antibiotic resistance protein (inferred from 64% identity to mtt:Ftrac_3723)

Predicted SEED Role

"Multiple antibiotic resistance protein marC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FZA9 at UniProt or InterPro

Protein Sequence (192 amino acids)

>Echvi_1812 membrane protein, MarC family (Echinicola vietnamensis KMM 6221, DSM 17526)
MFDFKEVISVSLILFSVIDILGSIPIIINLRRKSGHIQSEKATIVAGILMVLFLLLGKNI
LNLFGIGVDDFAIAGALIIFALGAEMILGVEIFKPDPEADASSTSIVPIAFPLIAGAGTM
TTILTLKAEFHQINIAIGILINLVVVYMVLKSTTWLERKLGKTGLDVLRRIFGIILLSIA
IKIFKTNLFDNF