Protein Info for Echvi_1645 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1219 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 665 to 688 (24 residues), see Phobius details PF07494: Reg_prop" amino acids 40 to 63 (24 residues), 25 bits, see alignment (E = 4.4e-09) amino acids 185 to 207 (23 residues), 15.3 bits, see alignment (E = 6.6e-06) amino acids 232 to 255 (24 residues), 19.9 bits, see alignment (E = 2e-07) amino acids 277 to 299 (23 residues), 17.6 bits, see alignment (E = 1.2e-06) amino acids 322 to 340 (19 residues), 18.2 bits, see alignment (E = 7.6e-07) PF07495: Y_Y_Y" amino acids 597 to 661 (65 residues), 62.7 bits, see alignment 8.8e-21 PF00512: HisKA" amino acids 705 to 770 (66 residues), 40.5 bits, see alignment 8.3e-14 PF02518: HATPase_c" amino acids 817 to 929 (113 residues), 93.4 bits, see alignment E=4.3e-30 PF00072: Response_reg" amino acids 970 to 1080 (111 residues), 80.1 bits, see alignment E=5e-26 PF12833: HTH_18" amino acids 1135 to 1213 (79 residues), 70.8 bits, see alignment 3.5e-23

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FZ37 at UniProt or InterPro

Protein Sequence (1219 amino acids)

>Echvi_1645 Signal transduction histidine kinase (Echinicola vietnamensis KMM 6221, DSM 17526)
MPKAPHIHLLCSLLTLLFSAGEVCGQQLHLKFDQLTVDNGLPQNSVYSIAKDKYGFMWFG
TWGGAVRYDGYNVQVFRANEKDSTALSDNRISGIVTDSLQNIWIEVEPHGALFQFDYQTE
SFHRPREGQVPDYLREKLLKRYSYHTKYASNQQYEWQTSDYGLVQINKTTHDTLIYHADA
RNPMSLSDHLVKDVYLDDNGHLWVGTQSGGVDHADLYDKAFKNYYKGRRGEGLIDNVARA
ICMDQSGRLWIGSENQGITILSFDHATPSYSYIGGKNLPDLRIRTLFCDTKGRVWIGTKK
GLFYFDPKKQEFTSCTMDMCHPSVFSITEDHNGTIWVGTFYGLASYDPQTDKFHCLSTTN
GLAGNQIMDLLMDHKGQLWAATEDGGISCIKNPVPYSNEQDITNYRHNSAPGNRLLSNRV
FSLAEDHLGHIWAASDAGLNCIYPDQQSIQHYSTSNGLIDDLTMAVAFDGSHSIWTSHTK
GLSRLDLATNKIQHFNRKDGLQGNEFKQSAVFRNPTDHRLYFGGSNGMTTFIPSQIKTNP
NPPNMALTRLSVMHQELNIGTKVRDRVILKSSLLTTEAITLTWWEKSFQVEFAAIHFTNP
LSNKYQYKLEGYDEAWITTDATRRIASYANLPPGEYTFKVLGANSDGVWSESPAMLKIIV
LTPWWLSWWAVCFYFMVVACVVWLVYRYLDSKIQLRKKEAIHHSKLQFFTEISHEFRTPL
TLIIDPLDRLIHEKPKKQLAEHYYHLMRNNAQQLLMLINQLLDFRKLEAGKLRLNLQSID
IVPFVKKTVASFEHLAEKKDIALGVETTLSSYPIRIDEDKITMVLNNLLSNALKFTPSQG
KVQVSLRPEEGTAKGVYIEVKDSGPGIPKAEQENVFGIFYQVKNGKARSEGSGIGLALTK
ELVVLHGGEISIESSLGKGTTLGFFLPDTSSAPQSSRKSKTPEEASSPVSAEMESFTIDQ
PAPGDAPLLLLVDDNEEIKSYIKMHLQGQYTIITAANGREGVAKAFDNIPDLIISDVMMP
DMHGLQLCQQLKTDMRTSHIPIILLTAKQSDEAKSEGYGTGADSYVTKPFSTQVLKARIK
NLLDQRQHLQVKFASASPEELPSCTANPVDKAFLENAREYIEHNLESEDLDVDSLAKKLN
MSRPQFYRKIKGLTDKSAAEFITSFRMEKASKLLRSGEFNVSETAYKVGYNLPNNFSRAF
IKHFGVSPSQYIKGKRKNT