Protein Info for Echvi_1599 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Superfamily II DNA and RNA helicases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 PF04851: ResIII" amino acids 20 to 149 (130 residues), 38.9 bits, see alignment E=1.8e-13 PF00270: DEAD" amino acids 22 to 177 (156 residues), 121.1 bits, see alignment E=8.1e-39 PF00271: Helicase_C" amino acids 218 to 323 (106 residues), 92.7 bits, see alignment E=3.5e-30 PF03880: DbpA" amino acids 365 to 435 (71 residues), 62.6 bits, see alignment E=5.9e-21

Best Hits

KEGG orthology group: None (inferred from 46% identity to sli:Slin_3331)

Predicted SEED Role

"ATP-dependent RNA helicase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FVE0 at UniProt or InterPro

Protein Sequence (438 amino acids)

>Echvi_1599 Superfamily II DNA and RNA helicases (Echinicola vietnamensis KMM 6221, DSM 17526)
MTLSNLNQQKVLQNLGISALNEMQEATLEATKKHANLMLIAPTGSGKTLAYLLSLLTKLE
EKDGIQALILAPTRELVLQIESVLKNMKLPIKINACYGGHMFSIERKNFSVPPSILVGTP
GRIKDHLERGTFSPDTIRHLIFDEFDKSLEMGFIGQMKYITGQLFQVTDKILVSATKAIE
VPYYLDFEDHFTLESQQTATTTLKTQKITTAKEGKLEGLLMLIRSLGSDQNAIVFANHRD
ACDRIGEFLDQHGVIFSLFRGGLEQDERESQLTKFRNGSTQVLIATDIAARGIDIPELDY
VVHFQLPPQETTYLHRNGRTARMKASGTCILMMTEGDYLPHFLDEVPTEFSLAPQSQPIT
PAFVTLHINKGKKDKVNKIDLVGFFLQFDFMEKEDLGLIEVKDFFSYVAVKREKFKEAIA
ASKNQRIKRKAIKVSLAK