Protein Info for Echvi_1596 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Acyl dehydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 154 PF01575: MaoC_dehydratas" amino acids 12 to 130 (119 residues), 93.5 bits, see alignment E=7.4e-31 PF13452: FAS1_DH_region" amino acids 16 to 123 (108 residues), 31.3 bits, see alignment E=2.1e-11

Best Hits

Swiss-Prot: 45% identical to ECH1_MYCTO: Probable enoyl-CoA hydratase 1 (MT0138) from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

KEGG orthology group: None (inferred from 69% identity to psn:Pedsa_1615)

MetaCyc: 39% identical to 4-chloro-3-hydroxybutyryl-CoA dehydratase (Salinispora tropica)
4.2.1.-

Predicted SEED Role

"MaoC family protein"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FYM0 at UniProt or InterPro

Protein Sequence (154 amino acids)

>Echvi_1596 Acyl dehydratase (Echinicola vietnamensis KMM 6221, DSM 17526)
MSQLVINSFEEFEKYIGQSLGTSEYHKITQDQINKFADATLDHQWIHTDPEKAKSEGAFG
NTIAHGYLTLSLVPYLWEQIVKVNNLKMLVNYGIESFKFAQPVLVDSEVRLHASLANITN
LRGTVKTEMSIKLEIKDQKKPAFTGKLIFLYHFK