Protein Info for Echvi_1376 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Thiol-disulfide isomerase and thioredoxins

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 514 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF08534: Redoxin" amino acids 366 to 496 (131 residues), 38.6 bits, see alignment E=2.4e-13 PF00578: AhpC-TSA" amino acids 367 to 490 (124 residues), 41.4 bits, see alignment E=3.3e-14 PF02630: SCO1-SenC" amino acids 372 to 437 (66 residues), 29.6 bits, see alignment E=1.5e-10 PF13905: Thioredoxin_8" amino acids 390 to 489 (100 residues), 46.4 bits, see alignment E=1e-15

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FYD3 at UniProt or InterPro

Protein Sequence (514 amino acids)

>Echvi_1376 Thiol-disulfide isomerase and thioredoxins (Echinicola vietnamensis KMM 6221, DSM 17526)
MMRLLLLLFALIANPNKAFSQYENSQKMVSVTVRYDQATATDTLMLFVMNPLYGETPSLK
NPGKKIKATMDNEGLYKFSFKTNTGIGYYMVANLNPKEGRIYTEERFVKRARYLKKALTP
LLIYESGDNVKIQISKKKVLPTYETYDPIQLFDLSFSGEGATKLRVWTETYYIYRKIGGS
NKSFDSNQKYQDGYAKSAEAIKTYIEDHKDAMSPEAYELLMADALYKLYTPALKNGILRY
YKEAEEQLSSEELENIKKAYFENVRDVLPETDLSKETLARSYYYFRYLVRKNIVDSYFLN
GSEDPSQVFERIMSKYSGELRERMLTLFLYTSFGTRQFDKQLEKVIKIARTDYCQNMLTE
LKKRKTGREMVNFELEDQKGNIVSLSEFRGKVIVIDFWFTGCGACKWMFENVLKKAEEVY
QYNPSVKFISISVDGSRRVWENSLKKGGYTSDKAINLFTNGEGMSHPIVSSYNIRAYPTI
VIINKEGKIDSYDLSDIRKEDGFKALSNQIDKLL