Protein Info for Echvi_1058 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: metalloprotein, YbeY/UPF0054 family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 143 PF02130: YbeY" amino acids 13 to 135 (123 residues), 95.2 bits, see alignment E=1.4e-31 TIGR00043: rRNA maturation RNase YbeY" amino acids 37 to 136 (100 residues), 96.7 bits, see alignment E=4.3e-32

Best Hits

Swiss-Prot: 59% identical to YBEY_CYTH3: Endoribonuclease YbeY (ybeY) from Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)

KEGG orthology group: None (inferred from 61% identity to sli:Slin_5558)

Predicted SEED Role

"Metal-dependent hydrolase YbeY, involved in rRNA and/or ribosome maturation and assembly"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FTU3 at UniProt or InterPro

Protein Sequence (143 amino acids)

>Echvi_1058 metalloprotein, YbeY/UPF0054 family (Echinicola vietnamensis KMM 6221, DSM 17526)
MAINFFEEDIQFKLPQKNLTKRWLREIAKKEGFVIADLNYIFCSDEYLYQINLDYLDHDT
YTDIITFDNSEEQDTLEGDIFVSIERIRDNAKDQNVDSHKETIRVISHGLLHLCGYKDKT
KEEAKLMREKEDEAISLFFSTQP