Protein Info for Echvi_1012 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Zinc carboxypeptidase.

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 837 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF00246: Peptidase_M14" amino acids 44 to 213 (170 residues), 53.4 bits, see alignment E=1.6e-18

Best Hits

Predicted SEED Role

"Peptidase M14, carboxypeptidase A precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FW65 at UniProt or InterPro

Protein Sequence (837 amino acids)

>Echvi_1012 Zinc carboxypeptidase. (Echinicola vietnamensis KMM 6221, DSM 17526)
MKRRLLIIFSFLLLSLLAHGQTKSPQVFLGYPLGERFTPHHRIVDYFEHVAAHNENVILK
YYGETFEHRPLLVVWVSAQENIDQLEEIRIDNLRRTGLEKGNPTTSVPITWLSYNVHGNE
AVSSEAAMKTLWALVDPAKGENKAWLQNNLVVIDPCVNPDGRDRYVNWYNQKMNVPLQPD
LQSIEHQEPWPGGRANHYLFDLNRDWAWQTQQESQQRMTLYQQWMPNIHLDFHEQGINSP
YYFAPAAIPLHPQLSDYQMEFQETFGRQNAAYFDQHNWFYFTKEVFDLLYPSYGDTYPMF
NGAIGMTIEQGGSGAAGIGVHTAEGDTLTLKERIRHHHTTGMTAIEVASKNAKTLLEEFS
RYFEPSPKGKYTSFVIKGDNSAGRITGLLSLLDKNHIQYRLSGKTANLQGFSYQKGQKSS
FSLEKDDIIVNAWQPKSVLTQVLFEPEAQLQDSLTYDITSWALPYAYGVEAYALQEKLEG
NTTYPQQEPVKNDVDKSALAYIVPWQDASEAIFLAALLQEDIRVRSASYPFTVDGQTYPT
GSLIITRGGNEYVKDFHQKVVTLANTHQIVLGTASTGFMDKGKDFGSRSVKTIKAPKVGV
FSGEGVSSLNFGEVWHFFEQQLQYPISVLEASAINHLNLTAYDELILPSGSYDWNDKALE
KLNEWTQAGGKLIVIESALDLFVDKDGFDLSTYLSDQQQEDYLPEASSDDSTTSPYRERE
RQAISDYAAGAVFEVDMDSTYALGYGTGGKYYTLKNNPTRYAFLNNGINAGVIHSLDQHR
SGFIGYRAKAKMKESLVFGVENRGKGQLVYLVDNPLFRSFWENGKLIMANAVFLVGN