Protein Info for Echvi_1011 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Uncharacterized protein conserved in bacteria

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13454: NAD_binding_9
  • amino acids 6 to 167 (162 residues), 103.9 bits, E=4.3e-34

Best Hits

KEGG orthology group: None (inferred from 46% identity to dfe:Dfer_5540)

Predicted SEED Role

"Hydroxyacylglutathione hydrolase (EC 3.1.2.6)" in subsystem Glutathione: Non-redox reactions or Methylglyoxal Metabolism (EC 3.1.2.6)

MetaCyc Pathways

• methylglyoxal degradation I (2/3 steps found)
• methylglyoxal degradation VIII (2/3 steps found)
• superpathway of methylglyoxal degradation (5/8 steps found)

KEGG Metabolic Maps

• Pyruvate metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.2.6

Sequence Analysis Tools

See L0FVE6 at UniProt or InterPro

Protein Sequence (502 amino acids)

>Echvi_1011 Uncharacterized protein conserved in bacteria (Echinicola vietnamensis KMM 6221, DSM 17526)
MKNITIIGGGANGISAFIELFIHIVTSGLEKEVQVTIVEKDERLGYGLAFGTPQPGHILN
TQADLMGIFAHEPGHFAAWLKKKGHRQREDLKGTDEVDNAYTTRIFYGDYIAEQADRYLK
MARSRGFVVEVVKGYAVDMEMDAGSYRVMLENGEAIPSDFVILALGTPKPNNFSKFQKRP
EYVDFPWPTSRLKSTIPGDAHVGVLGTSLSAIDTVMTLVDNDHRGKISLFSPDGLLPRVQ
PLENKTYQRIYLTLHNIHSIKRKTLQKPRVKTLLRLFMEEVAHYEGHPVDWRQFTARLSS
PEALLAWDISCAEEGGDALLNIADALRYDASTIWSWMDTDQKLLFKKWVGSDWAINRHPM
PLHNAKKLRKLFDQGQLEVCAMKDGDAVSYQQGTFGIKTSQKERVTVDFLVNATGSSSAL
AQMESPLIHKLLERNYIQPYEVGGAVLNERTMQVISPKGGEGIYAVGHIANGILMDVNAV
WYNVKTIGTLARDIIFRLAEEG