Protein Info for Echvi_0916 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Glycogen debranching enzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 906 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF25788: Ig_Rha78A_N" amino acids 28 to 135 (108 residues), 115.6 bits, see alignment E=3.1e-37 PF08531: Bac_rhamnosid_N" amino acids 176 to 349 (174 residues), 178.6 bits, see alignment E=2.6e-56 PF05592: Bac_rhamnosid" amino acids 359 to 457 (99 residues), 113.9 bits, see alignment E=7.4e-37 PF17389: Bac_rhamnosid6H" amino acids 463 to 806 (344 residues), 357.3 bits, see alignment E=2.4e-110 PF17390: Bac_rhamnosid_C" amino acids 809 to 879 (71 residues), 65.2 bits, see alignment 9.7e-22

Best Hits

Predicted SEED Role

"Alfa-L-rhamnosidase (EC 3.2.1.40)" in subsystem L-rhamnose utilization (EC 3.2.1.40)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.40

Use Curated BLAST to search for 3.2.1.40

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FTF0 at UniProt or InterPro

Protein Sequence (906 amino acids)

>Echvi_0916 Glycogen debranching enzyme (Echinicola vietnamensis KMM 6221, DSM 17526)
MKRLTTLILLFFTMISVAISHPDQDIAVDHLKVEMLTNPAGIDVENPRLSWEIITETPST
YQQAYQVLVASDPSLLSPDKADLWNSGKVDAEESTNIRYAGEELDKDTKVYWKVKVWTNH
GESDWSERAHWILGLRYYKDWKGRWIGFDRAFPWEEVSTFPTLGARYFRDEFDIKKTVER
ATVYIMGLGLYELHLNGQKVGDAVLAPTPTDYTQNVKYNAYEVTDLLQENGANAVGVMLG
NGRYFTMRQHYKPYKIKNFGFPKLLFNLIIHYTDGSTEVISTSDQWKGTADGPIRNNNEY
DGEYYDANKEFIGWDQVGFDDSAWLQAEYVQEPVGDYEAQMNENMKVMQDVAPVSLEAIG
QDRYVLDMGQNMVGWLQMTVKGKKGDTVKLKFAESLQENGELFMTNLRDAKVTDTYVLKN
EEKVTWEPRFTYHGFRFVEISGYPGEPKIEDFMGKMVYDDIKTIGHFETSDPMLNHIYQN
AWWGIAGNYKGMPVDCPQRNERQPWLGDRAVGAHGESYMFDNVRLYKKWLDDIRLAQKAD
GALPDVAPAYWRYYSDNMTWPGTYLMIADMLYQQTGDTSVIRENYPAMKKWLGYMADRYM
TEDYIVTEDSYGDWVVPPPSIEAGTGQNADVKRPSALISTAYYYHFMEVMSRFATILGKH
EEIPSYQSLKEKVHEGFHEEFYHQGFYGDNKMTDNLLPLAFGMVPEDDRQRVFDQVVETI
QIKNNGHLSTGLIGTQWLMRTLSDYGRADLALKLATNTTFPSWGYMIENGATTIWELWHG
NVAKPTMNSQNHTMLLGDLTVWFYEYLAGIKAGADSPGFKVFELAPVFVEGLDSVKASFD
SPYGAIGSHWERKGEQITWKIKVPANTTAIVKMPISATGGILMNGEALRSGDMEVKLGSG
EYELVF