Protein Info for Echvi_0863 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Na+/H+ antiporter NhaD and related arsenite permeases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 508 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 69 to 89 (21 residues), see Phobius details amino acids 98 to 117 (20 residues), see Phobius details amino acids 129 to 150 (22 residues), see Phobius details amino acids 161 to 183 (23 residues), see Phobius details amino acids 195 to 217 (23 residues), see Phobius details amino acids 239 to 256 (18 residues), see Phobius details amino acids 287 to 304 (18 residues), see Phobius details amino acids 317 to 335 (19 residues), see Phobius details amino acids 354 to 375 (22 residues), see Phobius details amino acids 440 to 460 (21 residues), see Phobius details amino acids 481 to 507 (27 residues), see Phobius details PF16980: CitMHS_2" amino acids 66 to 505 (440 residues), 497.3 bits, see alignment E=3.7e-153

Best Hits

KEGG orthology group: None (inferred from 73% identity to mtt:Ftrac_2014)

Predicted SEED Role

"Probable transmembrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FWK5 at UniProt or InterPro

Protein Sequence (508 amino acids)

>Echvi_0863 Na+/H+ antiporter NhaD and related arsenite permeases (Echinicola vietnamensis KMM 6221, DSM 17526)
MKNIIIAFGIVWGAVFYTGSASLMAQNNHQTTEVSAHQEGHEDQKDHASDPHHADAHAEG
EAEHAHAPVWLVIPFVVLLLMIATGPLFYEHFWHHNYPKVAIILAALVVLYYIFAMHNTH
APVHALAEYLQFIALLASLYIASGGIMISIDKKSTPLANVTLLIVGSIIANLIGTTGASM
LLIRPFIRLNKNNIRAYHIIFFIFMVSNVGGSLTPIGDPPLFLGFLKGVPFFWTLEHNWP
AWIIALIILATAFFFIDKKLGCAANDDEIEDTTSYSNKISLIGSKNFLWLLIVIISVFLD
PNVLDWVPAIVYDGTKFSFIRELIMFSVAFFSYKFADKRAIKGNEFNFEPIREVAFIFIG
IFGTMMPALELVGNFAKSPAGAELITHNSLYWGTGLLSGFLDNAPTYLNFLAAAMASRGA
TISDVEMVRTFAMDGYHDSAFQLMAISIASVFFGAMTYIGNGPNFMVKSIAEQSGIKMPS
FFGYIIRFSIPILLPVLIITWLIFFAFV