Protein Info for Echvi_0708 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: transcription termination factor NusA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 415 PF08529: NusA_N" amino acids 6 to 128 (123 residues), 108.2 bits, see alignment E=3.1e-35 TIGR01953: transcription termination factor NusA" amino acids 7 to 345 (339 residues), 376.3 bits, see alignment E=6.3e-117 PF13184: KH_5" amino acids 234 to 301 (68 residues), 99.4 bits, see alignment E=9.8e-33

Best Hits

KEGG orthology group: K02600, N utilization substance protein A (inferred from 78% identity to mtt:Ftrac_2448)

Predicted SEED Role

"Transcription termination protein NusA" in subsystem NusA-TFII Cluster or Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FWF1 at UniProt or InterPro

Protein Sequence (415 amino acids)

>Echvi_0708 transcription termination factor NusA (Echinicola vietnamensis KMM 6221, DSM 17526)
MDAKVLIDSFAEFARSKNVDRPTMIRILEDVFRAMIRKKYETDENFDVIINADKGDLEIW
RIREIVDDNSEDIWDHDKISHSEAKKIEPDFEIGEETYERIELEDFGRRAVMMARQTLIQ
KIKDLEKDLLFQQYEELVGEIITAEVYQILGREMLLMDGEGNELILPKGEQIPKDRFRKG
DTIRSIVHKVEMVNGNPRIILSRTSPIFLERLFENEVPEVYDGLITIKKIVREPGERAKV
AVESYDDRIDPVGACVGMKGSRIHAVVRELQNENIDVINYTDNLELYVSRALSPAKVSSI
QANEEEKRLSVFLKPDQVSLAIGKGGYNIRLASRLVGYEIDVFRELSDYEEEEDVDLSEF
SDEIEGWIIEELKKTGLDTAKSVLALSKEDLTRRTELEEETIEEIFRILKQEFEQ