Protein Info for Echvi_0634 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Parvulin-like peptidyl-prolyl isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 671 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF13616: Rotamase_3" amino acids 131 to 237 (107 residues), 80 bits, see alignment E=3e-26 amino acids 232 to 344 (113 residues), 75.4 bits, see alignment E=8e-25 PF00639: Rotamase" amino acids 140 to 234 (95 residues), 85.3 bits, see alignment E=7.3e-28 amino acids 247 to 343 (97 residues), 80.6 bits, see alignment E=2e-26 PF13145: Rotamase_2" amino acids 169 to 238 (70 residues), 27.3 bits, see alignment E=8.6e-10 amino acids 241 to 353 (113 residues), 28.3 bits, see alignment E=4.2e-10

Best Hits

Predicted SEED Role

"Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8)" in subsystem Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FUD3 at UniProt or InterPro

Protein Sequence (671 amino acids)

>Echvi_0634 Parvulin-like peptidyl-prolyl isomerase (Echinicola vietnamensis KMM 6221, DSM 17526)
MKTTYQCLWVLGLLVACSPNSKVSQSTPLSDEPQYLLTVGNENVFAEEFMHMLSKNRAFD
KEEDKLSKTEFEENFELFLNYKLKVKEAEALGMDESVEFQREFTAFKEDLKQPYILETSL
QEGEIRKAYARMQEVVHAQHILLRFPANASREDSVAVYRMALKIKERASDGEAFTVLAME
YSQDPSVKSNKGDLGYFTSLQMVYPFEDAVYQLKPGQISDPVLTDFGYHVIKLLDRKPNP
GQVKVSHILIRTDPADPLSEDRARRKITDIYAALQKEDTSWEEVCQLFSEDTNTKEKGGE
LPWFGVGAFLKEFEEAAFGLSEIGEISSPVKTSYGYHIIRLEDEKPLASYEEMEESLKSK
ILRDSRSGLINSQVMAIQKSRYQFRENTPVITAARTAISEQSKSLKDLRNTYTAQNLMDS
TLFTIEEHGKTVADFVGFVERDEVVVKVGKRTPFDAWFGKFVETSLDQAEEADLLANNDD
FRLLVNEYREGILLFNLMNERVWQRALTDTAGLKEYFASHRDQYTWGARTEALIVSVLAP
EAAAPIKAFLTDKPYQPGLKTSLVDHLDSLSTLSYQVEEGVFEVENKPVLQEIEIQSGLQ
EVTVKNKRYIVLLGKQYPAGPKAFEETRGKVIQDYQEHLNETLISLLKQNFIIQVNEDEK
ARVENIVVGQH